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dc.contributor.authorHoseini-Yazdi, Hosein
dc.contributor.authorVincent, Stephen J
dc.contributor.authorCollins, Michael J
dc.contributor.authorRead, Scott A
dc.contributor.authorAlonso-Caneiro, David
dc.date.accessioned2020-03-20T00:45:27Z
dc.date.available2020-03-20T00:45:27Z
dc.date.issued2019
dc.identifier.issn0816-4622
dc.identifier.doi10.1111/cxo.12855
dc.identifier.urihttp://hdl.handle.net/10072/383690
dc.description.abstractBackground: The aim of this study was to examine the influence of B-scan averaging on choroidal thickness using wide-field enhanced-depth imaging optical coherence tomography. Methods: Six high-resolution trans-foveal horizontal enhanced-depth imaging line scans (spanning a 60° field) were acquired consecutively from the right eye of 10 healthy adults (mean age 30 ± 5 years), with each line scan an average of 10, 20, 30, 40, 50 or 100 B-scans, using the automated real-time image averaging and follow-up features of a Spectralis device. The impact of B-scan averaging on regional measures of wide-field choroidal thickness (across macular and peripheral regions) and their accuracy was investigated, assuming that averaging 100 B-scans would provide the most accurate estimate of choroidal thickness. Results: Regional estimates of wide-field choroidal thickness did not vary across the different B-scan averaging conditions (all p > 0.05). The mean choroidal thickness averaged across the full wide-field area exhibited the closest agreement to measures obtained with 100 averaged B-scans, when frame averaging exceeded 30 B-scans (95 per cent limits of agreement +10 to −7, +7 to −7 and +6 to −3 μm for 30, 40 and 50 averaged B-scans, respectively), compared to 10 and 20 averaged B-scans (95 per cent limits of agreement +13 to −8 and +13 to −6 μm, respectively; p < 0.01 and p < 0.02 compared to the accuracy of 50 averaged B-scans). Conclusion: Averaging 30 B-scans for an individual enhanced-depth imaging optical coherence tomography line scan provided accurate measures of choroidal thickness across a wide-field (60°) area in young healthy eyes. This information can assist in designing the volumetric scan protocols required for detailed examination of the macular and peripheral choroid.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley Blackwell
dc.relation.ispartofpagefrom320
dc.relation.ispartofpageto326
dc.relation.ispartofissue3
dc.relation.ispartofjournalClinical and Experimental Optometry
dc.relation.ispartofvolume102
dc.subject.fieldofresearchPhysical sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchOphthalmology and optometry
dc.subject.fieldofresearchcode51
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode3212
dc.titleImpact of image averaging on wide-field choroidal thickness measurements using enhanced-depth imaging optical coherence tomography
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Impact of image averaging on wide‐field choroidal thickness measurements using enhanced‐depth imaging optical coherence tomography, Clinical and Experimental Optometry, Volume 102, Issue 3, Pages 320-326, which has been published in final form at https://doi.org/10.1111/cxo.12855. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html)
gro.hasfulltextFull Text
gro.griffith.authorAlonso-Caneiro, David


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