dc.contributor.author | Hoseini-Yazdi, Hosein | |
dc.contributor.author | Vincent, Stephen J | |
dc.contributor.author | Collins, Michael J | |
dc.contributor.author | Read, Scott A | |
dc.contributor.author | Alonso-Caneiro, David | |
dc.date.accessioned | 2020-03-20T00:45:27Z | |
dc.date.available | 2020-03-20T00:45:27Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0816-4622 | |
dc.identifier.doi | 10.1111/cxo.12855 | |
dc.identifier.uri | http://hdl.handle.net/10072/383690 | |
dc.description.abstract | Background: The aim of this study was to examine the influence of B-scan averaging on choroidal thickness using wide-field enhanced-depth imaging optical coherence tomography. Methods: Six high-resolution trans-foveal horizontal enhanced-depth imaging line scans (spanning a 60° field) were acquired consecutively from the right eye of 10 healthy adults (mean age 30 ± 5 years), with each line scan an average of 10, 20, 30, 40, 50 or 100 B-scans, using the automated real-time image averaging and follow-up features of a Spectralis device. The impact of B-scan averaging on regional measures of wide-field choroidal thickness (across macular and peripheral regions) and their accuracy was investigated, assuming that averaging 100 B-scans would provide the most accurate estimate of choroidal thickness. Results: Regional estimates of wide-field choroidal thickness did not vary across the different B-scan averaging conditions (all p > 0.05). The mean choroidal thickness averaged across the full wide-field area exhibited the closest agreement to measures obtained with 100 averaged B-scans, when frame averaging exceeded 30 B-scans (95 per cent limits of agreement +10 to −7, +7 to −7 and +6 to −3 μm for 30, 40 and 50 averaged B-scans, respectively), compared to 10 and 20 averaged B-scans (95 per cent limits of agreement +13 to −8 and +13 to −6 μm, respectively; p < 0.01 and p < 0.02 compared to the accuracy of 50 averaged B-scans). Conclusion: Averaging 30 B-scans for an individual enhanced-depth imaging optical coherence tomography line scan provided accurate measures of choroidal thickness across a wide-field (60°) area in young healthy eyes. This information can assist in designing the volumetric scan protocols required for detailed examination of the macular and peripheral choroid. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Wiley Blackwell | |
dc.relation.ispartofpagefrom | 320 | |
dc.relation.ispartofpageto | 326 | |
dc.relation.ispartofissue | 3 | |
dc.relation.ispartofjournal | Clinical and Experimental Optometry | |
dc.relation.ispartofvolume | 102 | |
dc.subject.fieldofresearch | Physical sciences | |
dc.subject.fieldofresearch | Biomedical and clinical sciences | |
dc.subject.fieldofresearch | Ophthalmology and optometry | |
dc.subject.fieldofresearchcode | 51 | |
dc.subject.fieldofresearchcode | 32 | |
dc.subject.fieldofresearchcode | 3212 | |
dc.title | Impact of image averaging on wide-field choroidal thickness measurements using enhanced-depth imaging optical coherence tomography | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
dc.description.version | Accepted Manuscript (AM) | |
gro.rights.copyright | © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Impact of image averaging on wide‐field choroidal thickness measurements using enhanced‐depth imaging optical coherence tomography, Clinical and Experimental Optometry, Volume 102, Issue 3, Pages 320-326, which has been published in final form at https://doi.org/10.1111/cxo.12855. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html) | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Alonso-Caneiro, David | |