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dc.contributor.authorFletcher, Michael P
dc.contributor.authorO'Rourke, Rachael
dc.contributor.authorGaikwad, Niranjan
dc.contributor.authorWalters, Darren L
dc.contributor.authorHamilton-Craig, Christian
dc.date.accessioned2019-11-13T02:10:29Z
dc.date.available2019-11-13T02:10:29Z
dc.date.issued2018
dc.identifier.issn2352-9067
dc.identifier.doi10.1016/j.ijcha.2018.03.005
dc.identifier.urihttp://hdl.handle.net/10072/384306
dc.description.abstractBackground: It was hypothesized that the accuracy of coronary CT angiography would be affected by case volume of the referring sites. Methods: The positive predictive value (PPV) of CTCA performed at a tertiary hospital specialising in cardiothoracic medicine and services with lower case-volumes were calculated. The tertiary hospital used as the high case-volume reference centre was The Prince Charles Hospital, which performed >1500 CTCA scans per annum over the study period. The low case-volume services used in the study were suburban radiology services, each with <500 cases per year. The PPV of positive CTCA at the reference site was compared to the pooled PPV of all other sites as a combined cohort, using invasive angiography as the reference standard. 512 scans were included, n = 199 subjects in the reference centre cohort, and n = 311 subjects in the pooled community radiology practice cohort. Results: The positive predictive value (PPV) of the high case-volume group (n = 199) was 0.7538 . The PPV of the pooled low case-volume services (n = 589) was 0.7331 , p = 0.604, with no statistically significant difference in positive predictive values. Conclusions: There was no significant difference in PPV between the two groups. This suggests that high-volume and lower-volume sites both have high PPV in Australia, above the published pooled PPV of four large prospective diagnostic accuracy studies (Miller et al., 2008; Budoff et al., 2008; Meijboom et al., 2008; Achenbach, 2007).
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom46
dc.relation.ispartofpageto49
dc.relation.ispartofjournalIJC Heart & Vasculature
dc.relation.ispartofvolume20
dc.subject.fieldofresearchCardiorespiratory Medicine and Haematology
dc.subject.fieldofresearchcode1102
dc.titleCoronary CT in Australia has high positive predictive value unaffected by site volume: An analysis of 510 positive CTCA scans with invasive angiographic correlation
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2018 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorHamilton-Craig, Christian


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