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dc.contributor.authorMaroules, Christopher D
dc.contributor.authorHamilton-Craig, Christian
dc.contributor.authorBranch, Kelley
dc.contributor.authorLee, James
dc.contributor.authorCury, Roberto C
dc.contributor.authorMaurovich-Horvat, Pal
dc.contributor.authorRubinshtein, Ronen
dc.contributor.authorThomas, Dustin
dc.contributor.authorWilliams, Michelle
dc.contributor.authorGuo, Yanshu
dc.contributor.authorCury, Ricardo C
dc.date.accessioned2019-07-04T12:33:33Z
dc.date.available2019-07-04T12:33:33Z
dc.date.issued2018
dc.identifier.issn1934-5925
dc.identifier.doi10.1016/j.jcct.2017.11.014
dc.identifier.urihttp://hdl.handle.net/10072/384308
dc.description.abstractBackground The Coronary Artery Disease Reporting and Data System (CAD-RADS) provides a lexicon and standardized reporting system for coronary CT angiography. Objectives: To evaluate inter-observer agreement of the CAD-RADS among an panel of early career and expert readers. Methods: Four early career and four expert cardiac imaging readers prospectively and independently evaluated 50 coronary CT angiography cases using the CAD-RADS lexicon. All readers assessed image quality using a five-point Likert scale, with mean Likert score ≥4 designating high image quality, and <4 designating moderate/low image quality. All readers were blinded to medical history and invasive coronary angiography findings. Inter-observer agreement for CAD-RADS assessment categories and modifiers were assessed using intra-class correlation (ICC) and Fleiss' Kappa (κ).The impact of reader experience and image quality on inter-observer agreement was also examined. Results: Inter-observer agreement for CAD-RADS assessment categories was excellent (ICC 0.958, 95% CI 0.938–0.974, p < 0.0001). Agreement among expert readers (ICC 0.925, 95% CI 0.884–0.954) was marginally stronger than for early career readers (ICC 0.904, 95% CI 0.852–0.941), both p < 0.0001. High image quality was associated with stronger agreement than moderate image quality (ICC 0.944, 95% CI 0.886–0.974 vs. ICC 0.887, 95% CI 0.775–0.95, both p < 0.0001). While excellent inter-observer agreement was observed for modifiers S (stent) and G (bypass graft) (both κ = 1.0), only fair agreement (κ = 0.40) was observed for modifier V (high risk plaque). Conclusion: Inter-observer reproducibility of CAD-RADS assessment categories and modifiers is excellent, except for high-risk plaque (modifier V) which demonstrates fair agreement. These results suggest CAD-RADS is feasible for clinical implementation.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier Science
dc.relation.ispartofpagefrom125
dc.relation.ispartofpageto130
dc.relation.ispartofissue2
dc.relation.ispartofjournalJOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
dc.relation.ispartofvolume12
dc.subject.fieldofresearchCardiorespiratory Medicine and Haematology
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode1102
dc.subject.fieldofresearchcode1103
dc.titleCoronary artery disease reporting and data system (CAD-RADS (TM)): Inter-observer agreement for assessment categories and modifiers
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorHamilton-Craig, Christian


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