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dc.contributor.authorBranch, Kelley R
dc.contributor.authorHamilton-Craig, Christian
dc.date.accessioned2019-05-29T12:45:03Z
dc.date.available2019-05-29T12:45:03Z
dc.date.issued2018
dc.identifier.issn1936-878X
dc.identifier.doi10.1016/j.jcmg.2017.06.009
dc.identifier.urihttp://hdl.handle.net/10072/384309
dc.description.abstractCoronary computed tomography angiography (CTA) is well known to have high sensitivity and negative predictive value to rule out anatomic coronary artery disease, but can have a relatively low specificity to detect obstructive coronary disease and ischemia (1). Accurate predictions of physiologic myocardial blood flow determined on the basis of anatomic coronary artery stenosis, be it from coronary CTA or from invasive coronary angiography, have been in a quandary for decades. Numerous previous studies have shown only an average correlation between angiographic stenosis and measures of ischemia such as myocardial perfusion imaging (MPI) assessments with positron emission tomography (PET), cardiac magnetic resonance (CMR), or invasive fractional flow reserve (FFR) 2, 3, 4. Despite this finding, angiographic stenosis evaluation remains the most common decision point for whether a patient receives further study or treatment. Thus, contrast dye does not lie with regard to the presence of coronary stenosis, but it is then challenged to identify myocardial ischemia.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier Science
dc.relation.ispartofpagefrom600
dc.relation.ispartofpageto602
dc.relation.ispartofissue4
dc.relation.ispartofjournalJACC-CARDIOVASCULAR IMAGING
dc.relation.ispartofvolume11
dc.subject.fieldofresearchCardiovascular medicine and haematology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3201
dc.subject.fieldofresearchcode3202
dc.titleThe Dye Don't Lie But May Not Tell the Truth Combining Coronary Computed Tomography Angiography With Myocardial Perfusion Imaging
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorHamilton-Craig, Christian


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