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dc.contributor.authorRamaraju, GA
dc.contributor.authorTeppala, S
dc.contributor.authorPrathigudupu, K
dc.contributor.authorKalagara, M
dc.contributor.authorThota, S
dc.contributor.authorKota, M
dc.contributor.authorCheemakurthi, R
dc.date.accessioned2019-08-22T00:54:14Z
dc.date.available2019-08-22T00:54:14Z
dc.date.issued2018
dc.identifier.issn0303-4569
dc.identifier.doi10.1111/and.12888
dc.identifier.urihttp://hdl.handle.net/10072/384391
dc.description.abstractThere is awareness of likelihood of abnormal spermatozoa in obese men; however, results from previous studies are inconclusive. Advances in computer‐aided sperm analysis (CASA) enable precise evaluation of sperm quality and include assessment of several parameters. We studied a retrospective cohort of 1285 men with CASA data from our infertility clinic during 2016. Obesity (BMI ≥30) was associated with lower (mean ± SE) volume (−0.28 ± 0.12, p‐value = .04), sperm count (48.36 ± 16.51, p‐value = .002), concentration (−15.83 ± 5.40, p‐value = .01), progressive motility (−4.45 ± 1.92, p‐value = .001), total motility (−5.50 ± 2.12, p‐value = .002), average curve velocity (μm/s) (−2.09 ± 0.85, p‐value = .001), average path velocity (μm/s) (−1.59 ± 0.75, p‐value = .006), and higher per cent head defects (0.92 ± 0.81, p‐value = .02), thin heads (1.12 ± 0.39, p‐value = .007) and pyriform heads (1.36 ± 0.65, p‐value = .02). Obese men were also more likely to have (odds ratio, 95% CI) oligospermia (1.67, 1.15–2.41, p‐value = .007) and asthenospermia (1.82, 1.20–2.77, p‐value = .005). This is the first report of abnormal sperm parameters in obese men based on CASA. Clinicians may need to factor in paternal obesity prior to assisted reproduction.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherWiley
dc.relation.ispartofissue3
dc.relation.ispartofjournalaNDROLOGIA
dc.relation.ispartofvolume50
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchPaediatrics and Reproductive Medicine
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1114
dc.titleAssociation between obesity and sperm quality
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorTeppala, Sri


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