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  • Ileus Management International (IMAGINE): protocol for a multicentre, observational study of ileus after colorectal surgery

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    Arthur179588.pdf (679.4Kb)
    Author(s)
    Chapman, SJ
    Arthur, T
    Chan, E
    Fomin, I
    Ho, D
    Morgan, S
    Schachtel, M
    Nabi, H
    Vasko, P
    Zabrak, R
    Orhalmi, J
    Larsen, H
    Nors, J
    Martensen, A
    Paramasivam, R
    Ravn, S
    Venara, A
    Frey, P-E
    Friedrich, M
    Raedeker, LB
    Mihaljevic, AL
    Farina, V
    Gavagna, L
    Lorenzon, L
    Pasquali, S
    Pata, F
    Pellino, G
    Podda, M
    Simioni, A
    Sgro, A
    Zaffaroni, G
    Schaeff, V
    Otto, A
    Sivins, A
    Ozolins, A
    Jakubauskas, M
    Poskus, T
    van Dalen, ASHM
    ten Doesschate, SFH
    van Elst, TR
    Kuiper, SZ
    Bemelman, WA
    Chu, MJJ
    Fagan, P
    Wells, CI
    Bissett, IP
    Joao, AA
    Soares, AS
    Carneiro, C
    Bautista, O Anabitarte
    El Kasmy, Y
    Perez-Ajates, S
    Espin-Basany, E
    Clerc, D
    Hubner, M
    Aktas, MK
    Baki, BE
    Ozkan, BB
    Sen, AY
    Yuksek, B
    Gecim, IE
    Bath, M
    Bhangu, A
    Borakati, A
    Fitzgerald, J Edward
    Glasbey, JCD
    Golding, D
    Goodson, R
    Kamarajah, S
    Khatri, C
    Khaw, R
    McLean, K
    Mills, E
    Nepogodiev, D
    Thakral, N
    Vaughan-Shaw, PG
    Yasin, I
    Pinkney, TD
    Chapman, SJ
    Blanco-Colino, R
    Hodson, J
    Griffith University Author(s)
    Arthur, Thomas
    Fomin, Igor
    Morgan, Samuel D.
    Schachtel, Michael J.
    Year published
    2018
    Metadata
    Show full item record
    Abstract
    Aim: The management of postoperative ileus following colorectal surgery remains controversial. It is the commonest complication after elective colorectal resection and is associated with an increased incidence of postoperative adverse events. The prevention and management of postoperative ileus remains unstandardized. This study aims to describe an international profile of gastrointestinal recovery after colorectal surgery and will assess the role of non‐steroidal anti‐inflammatory drugs, when used as postoperative analgesia, in expediting the return of gastrointestinal function. Methods: A multicentre, student‐ and ...
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    Aim: The management of postoperative ileus following colorectal surgery remains controversial. It is the commonest complication after elective colorectal resection and is associated with an increased incidence of postoperative adverse events. The prevention and management of postoperative ileus remains unstandardized. This study aims to describe an international profile of gastrointestinal recovery after colorectal surgery and will assess the role of non‐steroidal anti‐inflammatory drugs, when used as postoperative analgesia, in expediting the return of gastrointestinal function. Methods: A multicentre, student‐ and trainee‐led, prospective cohort study will be conducted across both Europe and Australasia. Adult patients undergoing elective colorectal resection during 2‐week data collection periods between January and April 2018 will be included. A site‐specific questionnaire will capture compliance to Enhanced Recovery after Surgery components at participating centres. The primary outcome is time to gastrointestinal recovery, measured using a composite outcome of bowel function and oral tolerance. The impact of non‐steroidal anti‐inflammatory drugs on gastrointestinal recovery will be evaluated along with safety data with respect to anastomotic leak, acute kidney injury and complications within 30 days of surgery. Discussion: This protocol describes the methodology of an international, observational assessment of gastrointestinal recovery after colorectal surgery. It discusses key challenges and describes how the results will impact on future investigation. The study will be conducted across a large student‐ and trainee‐led collaborative network, with prospective quality assurance and data validation strategies.
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    Journal Title
    Colorectal Disease
    Volume
    20
    Issue
    1
    DOI
    https://doi.org/10.1111/codi.13976
    Copyright Statement
    © 2018 The Association of Coloproctology of Great Britain and Ireland. This is the peer reviewed version of the following article: PIleus Management International (IMAGINE): protocol for a multicentre, observational study of ileus after colorectal surgery, Colorectal Disease, Volume 20, Issue 1, January 2018, Pages O17-O25, which has been published in final form at 10.1111/codi.13976. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html)
    Subject
    Clinical Sciences
    Publication URI
    http://hdl.handle.net/10072/384400
    Collection
    • Journal articles

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