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dc.contributor.authorShapla, Ummay
dc.contributor.authorRaihan, Jinat
dc.contributor.authorIslam, Asiful
dc.contributor.authorAlam, Fahmida
dc.contributor.authorSolayman, Naeem
dc.contributor.authorGan, Siew
dc.contributor.authorHossen, Sakib
dc.contributor.authorKhalil, Ibrahim
dc.date.accessioned2019-05-29T12:58:26Z
dc.date.available2019-05-29T12:58:26Z
dc.date.issued2018
dc.identifier.issn1214-021X
dc.identifier.doi10.1016/j.jab.2017.10.007
dc.identifier.urihttp://hdl.handle.net/10072/384456
dc.description.abstractHelicobacter pylori (H. pylori), which is found in the stomach of approximately 50% of humans, remains there for almost the entire lifetime of the infected individual, leading to various gastrointestinal tract-associated disorders following full-blown infection. Due to the emergence of antibiotic resistance, recurrence and high cost of therapy, most antibiotic-based treatment strategies are not very effective in eradicating H. pylori infections. The quest for an alternative treatment free of these inconveniences is currently in demand. One of the important alternatives is propolis, produced by the honeybee Apis mellifera, which has been used to treat different diseases since it possesses a wide range of biochemical properties. Propolis has been reported as a useful therapeutic regimen against H. pylori, which is an important cause of gastric inflammation, peptic ulcer, gastric cancer, and lymphomas of mucosa-associated lymphoid tissues. Apart from propolis, various active compounds of other natural products have also been confirmed to be effective. This review compiles the scientific evidence of the role of propolis and other natural products against H. pylori-associated gastrointestinal tract-related health complexities by acing as an anti-angiogenic, anti-inflammatory, and antioxidant factor as well as via modulation of enzymatic activities.
dc.description.peerreviewedYes
dc.languageen
dc.publisherUniversity of South Bohemia in Ceske Budejovice - Faculty of Health and Social Sciences
dc.relation.ispartofpagefrom81
dc.relation.ispartofpageto99
dc.relation.ispartofissue2
dc.relation.ispartofjournalJournal of Applied Biomedicine
dc.relation.ispartofvolume16
dc.subject.fieldofresearchBiological Sciences
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchcode06
dc.subject.fieldofresearchcode11
dc.titlePropolis: The future therapy against Helicobacter pylori-mediated gastrointestinal diseases
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.versionPost-print
gro.rights.copyright© The Author(s) YEAR. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International (CC BY-NC-ND 4.0) License (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorSolayman, Md.


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