dc.contributor.author | Mckay, Alannah KA | |
dc.contributor.author | Peeling, Peter | |
dc.contributor.author | Pyne, David B | |
dc.contributor.author | Welvaert, Marijke | |
dc.contributor.author | Tee, Nicolin | |
dc.contributor.author | Leckey, Jill J | |
dc.contributor.author | Sharma, Avish P | |
dc.contributor.author | Ross, Megan LR | |
dc.contributor.author | Garvican-Lewis, Laura A | |
dc.contributor.author | Swinkels, Dorine W | |
dc.contributor.author | Laarakkers, Coby M | |
dc.contributor.author | Burke, Louise M | |
dc.date.accessioned | 2019-07-04T12:35:41Z | |
dc.date.available | 2019-07-04T12:35:41Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0195-9131 | |
dc.identifier.doi | 10.1249/MSS.0000000000001816 | |
dc.identifier.uri | http://hdl.handle.net/10072/384651 | |
dc.description.abstract | PURPOSE:
The short-term restriction of carbohydrate (CHO) can potentially influence iron regulation via modification of postexercise interleukin-6 (IL-6) and hepcidin levels. This study examined the effect of a chronic ketogenic low-CHO high-fat (LCHF) diet on iron status and iron-regulatory markers in elite athletes.
METHODS:
International-level race walkers (n = 50) were allocated to one of three dietary interventions: (i) a high-CHO diet (n = 16), (ii) a periodized CHO availability (n = 17), or (iii) an LCHF diet (n = 17) while completing a periodized training program for 3 wk. A 19- to 25-km race walking test protocol was completed at baseline and after adaptation, and changes in serum ferritin, IL-6, and hepcidin concentrations were measured. Results from high-CHO and periodized CHO were combined into one group (CHO; n = 33) for analysis.
RESULTS:
The decrease in serum ferritin across the intervention period was substantially greater in the CHO group (37%) compared with the LCHF (23%) group (P = 0.021). After dietary intervention, the postexercise increase in IL-6 was greater in LCHF (13.6-fold increase; 95% confidence interval [CI] = 7.1-21.4) than athletes adhering to a CHO-rich diet (7.6-fold increase; 95% CI = 5.5-10.2; P = 0.033). Although no significant differences occurred between diets, CI values indicate that 3 h postexercise hepcidin concentrations were lower after dietary intervention compared with baseline in CHO (β = -4.3; 95% CI = -6.6 to -2.0), with no differences evident in LCHF.
CONCLUSION:
Athletes who adhered to a CHO-rich diet experienced favorable changes to the postexercise IL-6 and hepcidin response, relative to the LCHF group. Lower serum ferritin after 3 wk of additional dietary CHO might reflect a larger more adaptive hematological response to training. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | |
dc.publisher.uri | https://insights.ovid.com/crossref?an=00005768-201903000-00020&clickthrough=y | |
dc.relation.ispartofpagefrom | 548 | |
dc.relation.ispartofpageto | 555 | |
dc.relation.ispartofissue | 3 | |
dc.relation.ispartofjournal | MEDICINE AND SCIENCE IN SPORTS AND EXERCISE | |
dc.relation.ispartofvolume | 51 | |
dc.subject.fieldofresearch | Sports science and exercise | |
dc.subject.fieldofresearch | Medical physiology | |
dc.subject.fieldofresearch | Health services and systems | |
dc.subject.fieldofresearch | Public health | |
dc.subject.fieldofresearchcode | 4207 | |
dc.subject.fieldofresearchcode | 3208 | |
dc.subject.fieldofresearchcode | 4203 | |
dc.subject.fieldofresearchcode | 4206 | |
dc.title | Chronic Adherence to a Ketogenic Diet Modifies Iron Metabolism in Elite Athletes | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Sharma, Avish | |