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dc.contributor.authorPathirana, Dilan
dc.contributor.authorJohnston, Barbara
dc.contributor.authorJohnston, Peter
dc.date.accessioned2019-07-04T12:33:31Z
dc.date.available2019-07-04T12:33:31Z
dc.date.issued2019
dc.identifier.issn1025-5842
dc.identifier.doi10.1080/10255842.2018.1564821
dc.identifier.urihttp://hdl.handle.net/10072/384887
dc.description.abstractCoarctation of the Aorta is a congenital narrowing of the aorta and diagnosis can be difficult. Treatments result in idiopathic sequelae including hypertension. Untreated patients are known to develop increased arterial stiffness in the upper body, which worsens with time. We present results from simulations with a one-dimensional mathematical model, about the effect of stiffness, stenting, surgery and coarctation severity on blood pressure, Pulsatility and Resistivity Index. One conclusion is that increased stiffness may explain both hypertension in treated patients and why diagnosis can be difficult.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofpagefrom475
dc.relation.ispartofpageto489
dc.relation.ispartofissue5
dc.relation.ispartofjournalCOMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
dc.relation.ispartofvolume22
dc.subject.fieldofresearchBiomedical engineering
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode4003
dc.subject.fieldofresearchcode3203
dc.titleThe effect of including increased arterial stiffness in the upper body when modelling Coarctation of the Aorta
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorPathirana, Dilan
gro.griffith.authorJohnston, Barbara M.
gro.griffith.authorJohnston, Peter R.


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