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  • Bridging larger gaps in peripheral nerves using neural prosthetics and physical therapeutic agents

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    Sahar220931.pdf (460.3Kb)
    Author(s)
    Sahar, Muhammad Sana Ullah
    Barton, Matthew
    Tansley, Geoffrey Douglas
    Griffith University Author(s)
    Sahar, m
    Tansley, Geoff
    Barton, Matthew J.
    Year published
    2019
    Metadata
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    Abstract
    Peripheral nerve injuries are relatively common and can be caused by a variety of traumatic events such as motor vehicle accidents. They can lead to long-term disability, pain, and financial burden, and contribute to poor quality of life. In this review, we systematically analyze the contemporary literature on peripheral nerve gap management using nerve prostheses in conjunction with physical therapeutic agents. The use of nerve prostheses to assist nerve regeneration across large gaps (> 30 mm) has revolutionized neural surgery. The materials used for nerve prostheses have been greatly refined, making them suitable for ...
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    Peripheral nerve injuries are relatively common and can be caused by a variety of traumatic events such as motor vehicle accidents. They can lead to long-term disability, pain, and financial burden, and contribute to poor quality of life. In this review, we systematically analyze the contemporary literature on peripheral nerve gap management using nerve prostheses in conjunction with physical therapeutic agents. The use of nerve prostheses to assist nerve regeneration across large gaps (> 30 mm) has revolutionized neural surgery. The materials used for nerve prostheses have been greatly refined, making them suitable for repairing large nerve gaps. However, research on peripheral nerve gap management using nerve prostheses reports inconsistent functional outcomes, especially when prostheses are integrated with physical therapeutic agents, and thus warrants careful investigation. This review explores the effectiveness of nerve prostheses for bridging large nerve gaps and then addresses their use in combination with physical therapeutic agents.
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    Journal Title
    NEURAL REGENERATION RESEARCH
    Volume
    14
    Issue
    7
    DOI
    https://doi.org/10.4103/1673-5374.251186
    Copyright Statement
    © 2019 The Authors. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-Non-Commercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
    Subject
    Neurosciences
    Publication URI
    http://hdl.handle.net/10072/385084
    Collection
    • Journal articles

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