• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Sub-lethal photocatalysis bactericidal technology cause longer persistence of antibiotic-resistance mutant and plasmid through the mechanism of reduced fitness cost

    Author(s)
    Yin, Hongliang
    Chen, Xiaofang
    Li, Guiying
    Chen, Yongdi
    Wang, Wanjun
    An, Taicheng
    Wong, Po Keung
    Zhao, Huijun
    Griffith University Author(s)
    Zhao, Huijun
    Year published
    2019
    Metadata
    Show full item record
    Abstract
    Antibiotic-resistance bacteria (ARB) sustain longevity in environments representing a public health threat recently, but some current bactericidal technologies could eliminate ARB at endpoint of treatment. However, the intermediate process, where bacterial community might be shaped by a complex array of external stressor, was less to be investigated. Herein, the sub-lethal photocatalysis (Sub-PC) bactericidal technology was first applied to validate its effects on the fitness cost and fate of ARB mediated by mutations and antibiotic-resistance gene (ARG) encoded plasmid. Results revealed that the fitness cost of both two ...
    View more >
    Antibiotic-resistance bacteria (ARB) sustain longevity in environments representing a public health threat recently, but some current bactericidal technologies could eliminate ARB at endpoint of treatment. However, the intermediate process, where bacterial community might be shaped by a complex array of external stressor, was less to be investigated. Herein, the sub-lethal photocatalysis (Sub-PC) bactericidal technology was first applied to validate its effects on the fitness cost and fate of ARB mediated by mutations and antibiotic-resistance gene (ARG) encoded plasmid. Results revealed that the fitness cost of both two types of ARB decreased under Sub-PC conditions as compared with Luria-Broth (LB) broth condition. Plate counting revealed that antibiotic resistance mutant exhibited 6–7 days longer maintenance under the Sub-PC conditions than that under the LB condition. Besides, for plasmid-encoded ARB, the average abundance of ARG in bacteria community was maintained at 0.38 copies for ctx-1 and 0.58 copies for mcr-1 under the Sub-PC condition, which were higher than that under the LB condition (0.29 copies for ctx-1 and 0.45 copies for mcr-1). This study suggests that Sub-PC could cause longer-term maintenance of antibiotic resistance and provides an insightful understanding that how anthropogenic sterilization technologies or stressor may alleviate or spread bacterial antibiotic resistance.
    View less >
    Journal Title
    APPLIED CATALYSIS B-ENVIRONMENTAL
    Volume
    245
    DOI
    https://doi.org/10.1016/j.apcatb.2019.01.041
    Subject
    Physical chemistry
    Chemical engineering
    Environmental engineering
    Publication URI
    http://hdl.handle.net/10072/385209
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E
    • TEQSA: PRV12076

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander