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dc.contributor.authorTauro, Sharynen_US
dc.contributor.authorSu, Yung-Chanen_US
dc.contributor.authorThomas, Sandraen_US
dc.contributor.authorSchwarze, Yurgenen_US
dc.contributor.authorI. Matthaei, Klausen_US
dc.contributor.authorTownsend, Dijanaen_US
dc.contributor.authorSimson, Ljuboven_US
dc.contributor.authorA. Tripp, Ralphen_US
dc.contributor.authorMahalingam, S.en_US
dc.date.accessioned2017-04-24T13:32:10Z
dc.date.available2017-04-24T13:32:10Z
dc.date.issued2008en_US
dc.date.modified2011-05-03T04:46:48Z
dc.identifier.issn12864579en_US
dc.identifier.doi10.1016/j.micinf.2008.07.037en_AU
dc.identifier.urihttp://hdl.handle.net/10072/38527
dc.description.abstractThe aetiology of asthma associated with viral infection is complex. The dynamics that contribute to disease pathogenesis are multifactorial and involve overlapping molecular and cellular mechanisms, particularly the immune response to respiratory virus infection or allergen sensitization. This review summarizes the evidence associated with factors that may contribute to the development or exacerbation of asthma including age, host factors, genetic polymorphisms, altered immune responses, and aspects of viral antigen expression. This review also provides an important perspective of key events linked to the development of asthmatic disease and related pulmonary inflammation from human and animal studies, and discusses their relationship as targets for disease intervention strategies.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherElsevier Massonen_US
dc.publisher.placeFranceen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom1014en_US
dc.relation.ispartofpageto1023en_US
dc.relation.ispartofissue9en_US
dc.relation.ispartofjournalMicrobes and Infectionen_US
dc.relation.ispartofvolume10en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchVirologyen_US
dc.subject.fieldofresearchCellular Immunologyen_US
dc.subject.fieldofresearchcode060506en_US
dc.subject.fieldofresearchcode110704en_US
dc.titleMolecular and cellular mechanisms in the viral exacerbation of asthmaen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2008
gro.hasfulltextNo Full Text


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