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  • Levels of Hemolysis Markers in Erythrocyte Concentrates Administered Using a Syringe Infusion Pump

    Author(s)
    Gannam, Fernanda Figueiredo
    Belela-Anacleto, Aline Santa Cruz
    Kusahara, Denise Miyuki
    Pedreira, Mavilde Goncalves
    Griffith University Author(s)
    Pedreira, Mavilde
    Year published
    2018
    Metadata
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    Abstract
    Syringe infusion pumps (SIPs) led to major advances in infusion therapy and were gradually applied to the transfusion of packed red blood cells (RBCs), raising questions about possible cell damage. The objectives of this study were to determine levels of hematocrit (%), total hemoglobin (g/dL), free hemoglobin (g/dL), lactate dehydrogenase (units/L), potassium (mmol/L), the degree of hemolysis (%) of RBCs infused by an SIP, and to investigate the influence of the infusion rate. The experimental study comprised 14 RBCs, 3 SIPs, and infusion rates of 5, 10, and 20 mL/h. The results showed total hemoglobin reduction (P = .003), ...
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    Syringe infusion pumps (SIPs) led to major advances in infusion therapy and were gradually applied to the transfusion of packed red blood cells (RBCs), raising questions about possible cell damage. The objectives of this study were to determine levels of hematocrit (%), total hemoglobin (g/dL), free hemoglobin (g/dL), lactate dehydrogenase (units/L), potassium (mmol/L), the degree of hemolysis (%) of RBCs infused by an SIP, and to investigate the influence of the infusion rate. The experimental study comprised 14 RBCs, 3 SIPs, and infusion rates of 5, 10, and 20 mL/h. The results showed total hemoglobin reduction (P = .003), and increased free hemoglobin and hemolysis (P <.001) were identified. The conclusion reached was that RBCs presented changes in free hemoglobin and degree of hemolysis.
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    Journal Title
    JOURNAL OF INFUSION NURSING
    Volume
    41
    Issue
    3
    DOI
    https://doi.org/10.1097/NAN.0000000000000280
    Subject
    Nursing
    Publication URI
    http://hdl.handle.net/10072/385420
    Collection
    • Journal articles

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