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  • TEXT messages to improve MEDication adherence and Secondary prevention (TEXTMEDS) after acute coronary syndrome: a randomised clinical trial protocol

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    HAMILTON-CRAIG156413.pdf (793.8Kb)
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    Version of Record (VoR)
    Author(s)
    Chow, Clara K
    Thiagalingam, Aravinda
    Santo, Karla
    Kok, Cindy
    Thakkar, Jay
    Stepien, Sandrine
    Billot, Laurent
    Jan, Stephen
    Joshi, Rohina
    Hillis, Graham S
    Brieger, David
    Chew, Derek P
    Radholm, Karin
    Atherton, John J
    Bhindi, Ravinay
    Collins, Nicholas
    Coverdale, Steven
    Hamilton-Craig, Christian
    Kangaharan, Nadarajah
    Maiorana, Andrew
    McGrady, Michelle
    Shetty, Pratap
    Thompson, Peter
    Rogers, Anthony
    Redfern, Julie
    Griffith University Author(s)
    Hamilton-Craig, Christian
    Coverdale, Steven
    Year published
    2018
    Metadata
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    Abstract
    Background: Identifying simple, low-cost and scalable means of supporting lifestyle change and medication adherence for patients following a cardiovascular (CV) event is important. Objective: The TEXTMEDS (TEXT messages to improve MEDication adherence and Secondary prevention) study aims to investigate whether a cardiac education and support programme sent via mobile phone text message improves medication adherence and risk factor levels in patients following an acute coronary syndrome (ACS). Study: design A single-blind, multicentre, randomised clinical trial of 1400 patients after an ACS with 12 months follow-up. The ...
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    Background: Identifying simple, low-cost and scalable means of supporting lifestyle change and medication adherence for patients following a cardiovascular (CV) event is important. Objective: The TEXTMEDS (TEXT messages to improve MEDication adherence and Secondary prevention) study aims to investigate whether a cardiac education and support programme sent via mobile phone text message improves medication adherence and risk factor levels in patients following an acute coronary syndrome (ACS). Study: design A single-blind, multicentre, randomised clinical trial of 1400 patients after an ACS with 12 months follow-up. The intervention group will receive multiple weekly text messages that provide information, motivation, support to adhere to medications, quit smoking (if relevant) and recommendations for healthy diet and exercise. The primary endpoint is the percentage of patients who are adherent to cardioprotective medications and the key secondary outcomes are mean systolic blood pressure (BP) and low-density lipoprotein cholesterol. Secondary outcomes will also include total cholesterol, mean diastolic BP, the percentage of participants who are adherent to each cardioprotective medication class, the percentage of participants who achieve target levels of CV risk factors, major vascular events, hospital readmissions and all-cause mortality. The study will be augmented by formal economic and process evaluations to assess acceptability, utility and cost-effectiveness. Summary: The study will provide multicentre randomised trial evidence of the effects of a text message-based programme on cardioprotective medication adherence and levels of CV risk factors.
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    Journal Title
    BMJ OPEN
    Volume
    8
    Issue
    1
    DOI
    https://doi.org/10.1136/bmjopen-2017-019463
    Copyright Statement
    © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
    Subject
    Biomedical and clinical sciences
    Clinical sciences
    Other health sciences
    Publication URI
    http://hdl.handle.net/10072/385725
    Collection
    • Journal articles

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