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dc.contributor.authorChow, Clara K
dc.contributor.authorThiagalingam, Aravinda
dc.contributor.authorSanto, Karla
dc.contributor.authorKok, Cindy
dc.contributor.authorThakkar, Jay
dc.contributor.authorStepien, Sandrine
dc.contributor.authorBillot, Laurent
dc.contributor.authorJan, Stephen
dc.contributor.authorJoshi, Rohina
dc.contributor.authorHillis, Graham S
dc.contributor.authorBrieger, David
dc.contributor.authorChew, Derek P
dc.contributor.authorRadholm, Karin
dc.contributor.authorAtherton, John J
dc.contributor.authorBhindi, Ravinay
dc.contributor.authorCollins, Nicholas
dc.contributor.authorCoverdale, Steven
dc.contributor.authorHamilton-Craig, Christian
dc.contributor.authorKangaharan, Nadarajah
dc.contributor.authorMaiorana, Andrew
dc.contributor.authorMcGrady, Michelle
dc.contributor.authorShetty, Pratap
dc.contributor.authorThompson, Peter
dc.contributor.authorRogers, Anthony
dc.contributor.authorRedfern, Julie
dc.date.accessioned2019-06-21T05:24:14Z
dc.date.available2019-06-21T05:24:14Z
dc.date.issued2018
dc.identifier.issn2044-6055
dc.identifier.doi10.1136/bmjopen-2017-019463
dc.identifier.urihttp://hdl.handle.net/10072/385725
dc.description.abstractBackground: Identifying simple, low-cost and scalable means of supporting lifestyle change and medication adherence for patients following a cardiovascular (CV) event is important. Objective: The TEXTMEDS (TEXT messages to improve MEDication adherence and Secondary prevention) study aims to investigate whether a cardiac education and support programme sent via mobile phone text message improves medication adherence and risk factor levels in patients following an acute coronary syndrome (ACS). Study: design A single-blind, multicentre, randomised clinical trial of 1400 patients after an ACS with 12 months follow-up. The intervention group will receive multiple weekly text messages that provide information, motivation, support to adhere to medications, quit smoking (if relevant) and recommendations for healthy diet and exercise. The primary endpoint is the percentage of patients who are adherent to cardioprotective medications and the key secondary outcomes are mean systolic blood pressure (BP) and low-density lipoprotein cholesterol. Secondary outcomes will also include total cholesterol, mean diastolic BP, the percentage of participants who are adherent to each cardioprotective medication class, the percentage of participants who achieve target levels of CV risk factors, major vascular events, hospital readmissions and all-cause mortality. The study will be augmented by formal economic and process evaluations to assess acceptability, utility and cost-effectiveness. Summary: The study will provide multicentre randomised trial evidence of the effects of a text message-based programme on cardioprotective medication adherence and levels of CV risk factors.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBMJ PUBLISHING GROUP
dc.relation.ispartofissue1
dc.relation.ispartofjournalBMJ OPEN
dc.relation.ispartofvolume8
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchOther health sciences
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode4299
dc.titleTEXT messages to improve MEDication adherence and Secondary prevention (TEXTMEDS) after acute coronary syndrome: a randomised clinical trial protocol
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc/4.0/
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
gro.hasfulltextFull Text
gro.griffith.authorHamilton-Craig, Christian
gro.griffith.authorCoverdale, Steven


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