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  • The quest for mechanically and biologically functional soft biomaterials via soft network composites

    Author(s)
    Bas, Onur
    Catelas, Isabelle
    De-Juan-Pardo, Elena M
    Hutmacher, Dietmar W
    Griffith University Author(s)
    Hutmacher, Dietmar W.
    Year published
    2018
    Metadata
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    Abstract
    Developing multifunctional soft biomaterials capable of addressing all the requirements of the complex tissue regeneration process is a multifaceted problem. In order to tackle the current challenges, recent research efforts are increasingly being directed towards biomimetic design concepts that can be translated into soft biomaterials via advanced manufacturing technologies. Among those, soft network composites consisting of a continuous hydrogel matrix and a reinforcing fibrous network closely resemble native soft biological materials in terms of design and composition as well as physicochemical properties. This article ...
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    Developing multifunctional soft biomaterials capable of addressing all the requirements of the complex tissue regeneration process is a multifaceted problem. In order to tackle the current challenges, recent research efforts are increasingly being directed towards biomimetic design concepts that can be translated into soft biomaterials via advanced manufacturing technologies. Among those, soft network composites consisting of a continuous hydrogel matrix and a reinforcing fibrous network closely resemble native soft biological materials in terms of design and composition as well as physicochemical properties. This article reviews soft network composite systems with a particular emphasis on the design, biomaterial and fabrication aspects within the context of soft tissue engineering and drug delivery applications.
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    Journal Title
    ADVANCED DRUG DELIVERY REVIEWS
    Volume
    132
    DOI
    https://doi.org/10.1016/j.addr.2018.07.015
    Subject
    Pharmacology and pharmaceutical sciences
    Publication URI
    http://hdl.handle.net/10072/385754
    Collection
    • Journal articles

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