Clandestine Manufacture of 3,4-Methylenedioxyamphetamine (MDA) From Helional via α-Methyl-3,4-methylenedioxyphenylpropionitrile (MMDPPN)

Abstract

There appears to be an endless quest to circumvent existing legislation in the clandestine manufacture of dangerous drugs. One such pathway encountered in recent years is the conversion of unrestricted helional into 3,4-methylenedioxyamphetamine (MDA) by the “Twodogs” method... (redacted) ...The method provides a significant improvement in yield when compared to the “Twodogs” process.