Bidirectional relationship between methamphetamine use and positive psychotic symptoms in regular methamphetamine users: Evidence from a prospective cohort study

Hides, Leanne; Chan, Gary; Dawe, Sharon; McKetin, Rebecca; Kavanagh, David J.; Young, Ross McD.; Teesson, Maree; Saunders, John B.

doi:10.25904/5d5b7e54d38fe

Author(s)

Hides, Leanne

Chan, Gary

Dawe, Sharon

McKetin, Rebecca

Kavanagh, David J.

Young, Ross McD.

Teesson, Maree

Saunders, John B.

Griffith University Author(s)

Dawe, Sharon

Year published

2019-08

Metadata

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Abstract

Background: Methamphetamine (MA) has been consistently associated with positive psychotic symptoms, but little is known about whether the reverse also occurs. Aims: This study determined whether the relationship between MA use and positive psychotic symptoms is bidirectional over 12 months. The impact of lifetime psychotic disorders and MA dependence on these relationships was also examined. Method: 201 regular (at least monthly) primary MA users were recruited from free needle syringe programs in three Australian cities. Data on the frequency of MA and other drug use (Timeline Followback) and the severity of positive ...
View more >Background: Methamphetamine (MA) has been consistently associated with positive psychotic symptoms, but little is known about whether the reverse also occurs. Aims: This study determined whether the relationship between MA use and positive psychotic symptoms is bidirectional over 12 months. The impact of lifetime psychotic disorders and MA dependence on these relationships was also examined. Method: 201 regular (at least monthly) primary MA users were recruited from free needle syringe programs in three Australian cities. Data on the frequency of MA and other drug use (Timeline Followback) and the severity of positive psychotic symptoms (Brief Psychiatric Rating Scale) in the past 2 weeks were collected in 12 contiguous monthly face-to-face interviews (mean of 9.14/11 (SD=3.16) follow ups completed). Diagnoses were derived using the Psychiatric Research Interview for DSM-IV Substance and Mental Disorders.
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Journal Title

The British Journal of Psychiatry

DOI

https://doi.org/10.25904/5d5b7e54d38fe

Copyright Statement

Copyright is held by the creator, unless otherwise stated. This work is provided licensed under a Attribution-NonCommercial-NoDerivs 3.0 Australia License.

Item Access Status

Mediated access. Requests for access via the form in Data Link.

Note

Prof Sharon Dawe s.dawe@griffith.edu.au

Data coverage for 2006 - 2009.

MA users were recruited after collecting injecting equipment from free needle syringe programs in three Australian cities (Brisbane, Melbourne, Sydney).

All data de-identified. Custodian, Prof Sharon Dawe, who can be contacted at s.dawe@griffith.edu.au. Attribution: The original creator must be credited and the source linked to Not for commercial use: No Derivative Works: May not adapt or change the work in any way.

Leanne Hides, PhD(Clin),1* Gary Chan, PhD,1 Sharon Dawe, PhD,2 Rebecca McKetin, PhD,3 David J. Kavanagh, PhD,4 Ross McD. Young, PhD,4 Maree Teesson, PhD5 & John B. Saunders, MD1,6 1 Centre for Youth Substance Abuse Research, School of Psychology, The University of Queensland, Brisbane, Queensland, Australia 2 School of Applied Psychology, Griffith University, Brisbane, Queensland, Australia 3 National Drug & Alcohol Research Centre, University of New South Wales, Sydney, Australia 4 Centre for Children’s Health Research, Institute of Health and Biomedical Innovation, School of Psychology and Counselling, Queensland University of Technology (QUT), Brisbane, Queensland, Australia 5 The Matilda Centre, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia 6 Disciplines of Psychiatry and Addiction Medicine, Faculty of Medicine, University of Sydney, New South Wales, Australia

Subject

Health, Clinical and Counselling Psychology

929209

Mental Health Services

Methamphetamine

psychosis