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dc.contributor.authorBeissbarth, J
dc.contributor.authorBinks, MJ
dc.contributor.authorMarsh, RL
dc.contributor.authorChang, AB
dc.contributor.authorLeach, AJ
dc.contributor.authorSmith-Vaughan, HC
dc.date.accessioned2019-08-26T04:39:06Z
dc.date.available2019-08-26T04:39:06Z
dc.date.issued2018
dc.identifier.issn1756-0500
dc.identifier.doi10.1186/s13104-018-3429-z
dc.identifier.urihttp://hdl.handle.net/10072/386681
dc.description.abstractObjective: Haemophilus haemolyticus can be misidentified as nontypeable Haemophilus influenzae (NTHi) due to their phenotypic similarities in microbiological culture. This study aimed to determine the prevalence of misidentified NTHi in respiratory specimens from children living in northern Australia. Results: Among respiratory specimens collected in studies between 2010 and 2013, retrospective PCR analysis found that routine culture misidentified H. haemolyticus as NTHi in 0.3% (3/879) of nasal specimens, 25% (14/55) of bronchoalveolar lavage and 40% (12/30) of throat specimens. Therefore, in this population, PCR-based NTHi diagnostics are indicated for throat and bronchoalveolar specimens, but not for nasal specimens.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.relation.ispartofpagefrom323
dc.relation.ispartofissue1
dc.relation.ispartofjournalBMC Research Notes
dc.relation.ispartofvolume11
dc.subject.fieldofresearchOther Medical and Health Sciences
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode1199
dc.subject.fieldofresearchcode0601
dc.subject.keywordsHaemophilus haemolyticus (Hh)
dc.subject.keywordsNasopharynx, bronchoalveolar lavage
dc.subject.keywordsNontypeable Haemophilus influenzae (NTHi)
dc.titleRecommendations for application of Haemophilus influenzae PCR diagnostics to respiratory specimens for children living in northern Australia: a retrospective re-analysis.
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationBeissbarth, J; Binks, MJ; Marsh, RL; Chang, AB; Leach, AJ; Smith-Vaughan, HC, Recommendations for application of Haemophilus influenzae PCR diagnostics to respiratory specimens for children living in northern Australia: a retrospective re-analysis., BMC Research Notes, 2018, 11 (1), pp. 323-
dcterms.dateAccepted2018-05-10
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2019-08-26T04:35:43Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
gro.hasfulltextFull Text
gro.griffith.authorSmith-Vaughan, Heidi


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