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dc.contributor.authorHamilton-Craig, C
dc.contributor.authorStaeb, D
dc.contributor.authorO'Brien, K
dc.contributor.authorGalloway, G
dc.contributor.authorBarth, M
dc.date.accessioned2019-09-05T05:39:02Z
dc.date.available2019-09-05T05:39:02Z
dc.date.issued2018
dc.identifier.issn0195-668X
dc.identifier.doi10.1093/eurheartj/ehy565.1163
dc.identifier.urihttp://hdl.handle.net/10072/386960
dc.description.abstractBackground: Ultra-high-field (B0 ≥7 Tesla) cardiovascular magnetic resonance (CMR) offers increased resolution, but cardiac imaging requiring ECG gating is significantly impacted from the magneto-hydrodynamic (MHD) effect, distorts the ECG trace (1–3). Previously, 7T CMR was constrained to using pulse oximetry for triggering, We explored the technical feasbility of a 7 T research MR scanner using of-the-art ECG trigger algorithm to assess left and right ventricular volumes, aortic and pulmonary valve flow. Methods: 7T CMR scans were performed on 10 healthy volunteers on whole-body research MRI scanner (Siemens Healthcare, Erlangen, Germany) with 8 channel Tx/32 channel Rx cardiac coil (MRI Tools GmbH, Berlin, Germany) under institutional review board approval. Vectorcardiogram ECG was successfully performed using a learning phase outside of the magnetic field, with a trigger algorithm with sufficient accuracy for CMR despite severe ECG signal distortions from the 7T field. Cine CMR was performed after 3rd-order B0 shimming using a high-resolution breath-held ECG-retro-gated segmented two-dimensional spoiled gradient echo sequence, and 2-dimensional phase contrast flow imaging. Analysis was performed using Cmr42 software (Circle CVi, Calgary). Results: Successful 7T CMR scans were acquired in all patients (100%) using the Vectorcardiogram 3-lead ECG method. Image quality was sufficient to quantitate both left and right ventricular volumes, ejection fraction, aortic and pulmonary blood flow and regurgitant fractions in 9/10 (90%) of volunteers (figure 1), with one volunteer having difficulty with breath-holding and ventricular ectopy causing gating artefacts.
dc.languageEnglish
dc.publisherOxford University Press
dc.relation.ispartofconferencenameEuropean Society of Cardiology Congress (ESCC)
dc.relation.ispartofconferencetitleEuropean Heart Journal
dc.relation.ispartofdatefrom2018-08-25
dc.relation.ispartofdateto2018-08-29
dc.relation.ispartoflocationMunich, Germany
dc.relation.ispartofpagefrom233
dc.relation.ispartofpageto233
dc.relation.ispartofissuesuppl_1
dc.relation.ispartofvolume39
dc.subject.fieldofresearchCardiovascular medicine and haematology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3201
dc.subject.fieldofresearchcode3202
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsCardiac & Cardiovascular Systems
dc.subject.keywordsCardiovascular System & Cardiology
dc.title7-Tesla Cardiac MRI for Ventricular and Valvular quantitation in healthy volunteers
dc.typeConference output
dc.type.descriptionE3 - Conferences (Extract Paper)
dcterms.bibliographicCitationHamilton-Craig, C; Staeb, D; O'Brien, K; Galloway, G; Barth, M, 7-Tesla Cardiac MRI for Ventricular and Valvular quantitation in healthy volunteers, European Heart Journal, 2018, 39 (suppl_1), pp. 233-233
dc.date.updated2019-09-05T05:36:39Z
gro.hasfulltextNo Full Text
gro.griffith.authorHamilton-Craig, Christian


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