dc.contributor.author | Hamilton-Craig, C | |
dc.contributor.author | Staeb, D | |
dc.contributor.author | O'Brien, K | |
dc.contributor.author | Galloway, G | |
dc.contributor.author | Barth, M | |
dc.date.accessioned | 2019-09-05T05:39:02Z | |
dc.date.available | 2019-09-05T05:39:02Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 0195-668X | |
dc.identifier.doi | 10.1093/eurheartj/ehy565.1163 | |
dc.identifier.uri | http://hdl.handle.net/10072/386960 | |
dc.description.abstract | Background: Ultra-high-field (B0 ≥7 Tesla) cardiovascular magnetic resonance (CMR) offers increased resolution, but cardiac imaging requiring ECG gating is significantly impacted from the magneto-hydrodynamic (MHD) effect, distorts the ECG trace (1–3). Previously, 7T CMR was constrained to using pulse oximetry for triggering, We explored the technical feasbility of a 7 T research MR scanner using of-the-art ECG trigger algorithm to assess left and right ventricular volumes, aortic and pulmonary valve flow.
Methods: 7T CMR scans were performed on 10 healthy volunteers on whole-body research MRI scanner (Siemens Healthcare, Erlangen, Germany) with 8 channel Tx/32 channel Rx cardiac coil (MRI Tools GmbH, Berlin, Germany) under institutional review board approval. Vectorcardiogram ECG was successfully performed using a learning phase outside of the magnetic field, with a trigger algorithm with sufficient accuracy for CMR despite severe ECG signal distortions from the 7T field. Cine CMR was performed after 3rd-order B0 shimming using a high-resolution breath-held ECG-retro-gated segmented two-dimensional spoiled gradient echo sequence, and 2-dimensional phase contrast flow imaging. Analysis was performed using Cmr42 software (Circle CVi, Calgary).
Results: Successful 7T CMR scans were acquired in all patients (100%) using the Vectorcardiogram 3-lead ECG method. Image quality was sufficient to quantitate both left and right ventricular volumes, ejection fraction, aortic and pulmonary blood flow and regurgitant fractions in 9/10 (90%) of volunteers (figure 1), with one volunteer having difficulty with breath-holding and ventricular ectopy causing gating artefacts. | |
dc.language | English | |
dc.publisher | Oxford University Press | |
dc.relation.ispartofconferencename | European Society of Cardiology Congress (ESCC) | |
dc.relation.ispartofconferencetitle | European Heart Journal | |
dc.relation.ispartofdatefrom | 2018-08-25 | |
dc.relation.ispartofdateto | 2018-08-29 | |
dc.relation.ispartoflocation | Munich, Germany | |
dc.relation.ispartofpagefrom | 233 | |
dc.relation.ispartofpageto | 233 | |
dc.relation.ispartofissue | suppl_1 | |
dc.relation.ispartofvolume | 39 | |
dc.subject.fieldofresearch | Cardiovascular medicine and haematology | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearchcode | 3201 | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.keywords | Science & Technology | |
dc.subject.keywords | Life Sciences & Biomedicine | |
dc.subject.keywords | Cardiac & Cardiovascular Systems | |
dc.subject.keywords | Cardiovascular System & Cardiology | |
dc.title | 7-Tesla Cardiac MRI for Ventricular and Valvular quantitation in healthy volunteers | |
dc.type | Conference output | |
dc.type.description | E3 - Conferences (Extract Paper) | |
dcterms.bibliographicCitation | Hamilton-Craig, C; Staeb, D; O'Brien, K; Galloway, G; Barth, M, 7-Tesla Cardiac MRI for Ventricular and Valvular quantitation in healthy volunteers, European Heart Journal, 2018, 39 (suppl_1), pp. 233-233 | |
dc.date.updated | 2019-09-05T05:36:39Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Hamilton-Craig, Christian | |