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dc.contributor.authorSlomko, Joanna
dc.contributor.authorNewton, Julia L
dc.contributor.authorKujawski, Slawomir
dc.contributor.authorTafil-Klawe, Malgorzata
dc.contributor.authorKlawe, Jacek
dc.contributor.authorStaines, Donald
dc.contributor.authorMarshall-Gradisnik, Sonya
dc.contributor.authorZalewski, Pawel
dc.date.accessioned2019-09-06T02:29:02Z
dc.date.available2019-09-06T02:29:02Z
dc.date.issued2019
dc.identifier.issn2044-6055
dc.identifier.doi10.1136/bmjopen-2018-023955
dc.identifier.urihttp://hdl.handle.net/10072/386992
dc.description.abstractObjectives: The aim of this study was to estimate the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and describe illness characteristics in a community population in Poland. Design: cross-sectional study. Setting: Poland. Participants: Of the cohort of 1400 who self-presented with fatigue only 69 subsequently were confirmed as having CFS/ME using the Fukuda criteria. Main outcome measures: Participants completed the following screening symptom assessment tools: Chalder Fatigue Scale, Hospital Anxiety and Depression Scale (HADS), Epworth Sleepiness Scale (ESS), Composite Autonomic Symptom Score 31 (COMPASS 31), Quality of Life Scale (QOLS). Haemodynamic and autonomic parameters were automatically measured at rest with a Task Force Monitor. Results: In 1308, from 1400 (93%) individuals who identified themselves as fatigued, recognised chronic conditions were identified, for example, neurological (n=280, 21.5%), neurodegenerative (n=200, 15%), psychiatric (n=654, 50%) and immunologic (n=174, 13.5%) disorders. The remaining 69 participants (mean age 38.3±8.5) met the Fukuda defintion for CFS/ME and had baseline objective assessment. The majority had experienced symptoms for over 2 years with 37% having symptoms for 2–5 years and 21.7% for more than 10 years. The COMPASS 31 indicated that 50% have symptoms consistent with orthostatic intolerance. About 43/69 (62%) had Epworth sleepiness scores ≥10, ie, consistent with excessive daytime sleepiness, 26/69 (38%) had significant anxiety and 22/69 (32%) depression measured by HADS A & D. Quality of life is significantly impaired in those with Fukuda criteria CFS (QLS score 64±11) with significant negative relationships between quality of life and fatigue (p<0.0001), anxiety (p=0.0009), depression (p<0.0001) and autonomic symptoms (p=0.04). Conclusion: This is the first study to summarise illness characteristics of Polish CFS/ME patients. Our study has confirmed that fatigue is a common and under-recognised symptom affecting the Polish population.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBMJ Publishing
dc.relation.ispartofissue3
dc.relation.ispartofjournalBMJ Open
dc.relation.ispartofvolume9
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchOther Medical and Health Sciences
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1117
dc.subject.fieldofresearchcode1199
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsMedicine, General & Internal
dc.subject.keywordsGeneral & Internal Medicine
dc.titlePrevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationSlomko, J; Newton, JL; Kujawski, S; Tafil-Klawe, M; Klawe, J; Staines, D; Marshall-Gradisnik, S; Zalewski, P, Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study, BMJ Open, 2019, 9 (3)
dcterms.licensehttp://creativecommons.org/licenses/by-nc/4.0/
dc.date.updated2019-09-06T02:25:50Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s). Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.
gro.hasfulltextFull Text
gro.griffith.authorSlomko, Joanna
gro.griffith.authorZalewski, Pawel
gro.griffith.authorMarshall-Gradisnik, Sonya M.
gro.griffith.authorStaines, Donald R.


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