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dc.contributor.authorMousa, Hamouda M
dc.contributor.authorAbdal-hay, Abdalla
dc.contributor.authorBartnikowski, Michal
dc.contributor.authorMohamed, Ibrahim MA
dc.contributor.authorYasin, Ahmed S
dc.contributor.authorIvanovski, Saso
dc.contributor.authorPark, Chan Hee
dc.contributor.authorKim, Cheol Sang
dc.date.accessioned2019-09-09T01:10:30Z
dc.date.available2019-09-09T01:10:30Z
dc.date.issued2018
dc.identifier.issn2373-9878
dc.identifier.doi10.1021/acsbiomaterials.8b00277
dc.identifier.urihttp://hdl.handle.net/10072/387045
dc.description.abstractIn the present work, magnesium (Mg) AZ31 alloy was coated with a multifunctional membrane layer composed of ZnO nanoparticles (NPs) embedded in a poly(lactic acid) (PLA) matrix. We aimed to produce a stable coating that would be used to control the degradation rate of the Mg alloy and promote a local antibacterial activity. ZnO NPs were dispersed at 5 and 10 wt % in a PLA solution and dip-coated onto the AZ31 substrate. Surface topography, chemical composition, thickness, electrochemical corrosion performance, mass variation, antibacterial activity, adhesion performance, and cytotoxicity of an uncoated control and coated alloys were investigated. The results indicated that the incorporation of ZnO NPs at various concentrations affords a dramatic control over surface topography and degradation rates under in vitro and in vivo environmental conditions when compared to the uncoated Mg alloy control. In addition, the results confirmed that the coated layer exerts antibacterial properties and supports cell growth, indicating this system may have utility for bone tissue engineering applications.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Chemical Society (ACS Publications)
dc.relation.ispartofpagefrom2169
dc.relation.ispartofpageto2180
dc.relation.ispartofissue6
dc.relation.ispartofjournalACS Biomaterials Science and Engineering
dc.relation.ispartofvolume4
dc.subject.fieldofresearchBiomedical Engineering
dc.subject.fieldofresearchcode0903
dc.subject.keywordsScience & Technology
dc.subject.keywordsTechnology
dc.subject.keywordsMaterials Science, Biomaterials
dc.subject.keywordsbiodegradable magnesium alloy
dc.titleA Multifunctional Zinc Oxide/Poly(Lactic Acid) Nanocomposite Layer Coated on Magnesium Alloys for Controlled Degradation and Antibacterial Function
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationMousa, HM; Abdal-hay, A; Bartnikowski, M; Mohamed, IMA; Yasin, AS; Ivanovski, S; Park, CH; Kim, CS, A Multifunctional Zinc Oxide/Poly(Lactic Acid) Nanocomposite Layer Coated on Magnesium Alloys for Controlled Degradation and Antibacterial Function, ACS Biomaterials Science and Engineering, 2018, 4 (6), pp. 2169-2180
dc.date.updated2019-09-09T01:08:58Z
gro.hasfulltextNo Full Text
gro.griffith.authorBartnikowski, Michal
gro.griffith.authorIvanovski, Saso


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