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dc.contributor.authorWunner, Felix M
dc.contributor.authorEggert, Sebastian
dc.contributor.authorMaartens, Joachim
dc.contributor.authorBas, Onur
dc.contributor.authorDalton, Paul D
dc.contributor.authorDe-Juan-Pardo, Elena M
dc.contributor.authorHutmacher, Dietmar W
dc.date.accessioned2019-09-10T00:50:23Z
dc.date.available2019-09-10T00:50:23Z
dc.date.issued2019
dc.identifier.issn2329-7662
dc.identifier.doi10.1089/3dp.2017.0149
dc.identifier.urihttp://hdl.handle.net/10072/387142
dc.description.abstractThree-dimensionally (3D) printed scaffolds and cell culture lattices with microscale features are increasingly being used in tissue engineering and regenerative medicine. One additive manufacturing technology used to design and fabricate such structures is melt electrowriting (MEW), a process which needs to be scaled in production to effectively translate to industrial applications. In this study, a scale-up printer, designed with eight simultaneously extruding heads, is constructed and validated. Importantly, identical structures could be fabricated using parameters developed from a single-head system, therefore establishing a MEW printer ecosystem that allows for direct upscaling from laboratory research. The successful transfer to vertically mounted collectors produced homogeneous reproducible scaffolds with identical morphologies and fiber diameters. These proof-of-concept experiments also show that MEW is capable of large-scale fabrication, successfully demonstrated by manufacturing 780 × 780-mm sheets of scaffolds/lattices. This study demonstrates that upscaling MEW can be realized by multiplying the number of print heads, while vertical mounting of the collector significantly reduces the MEW footprint. Additionally, economic aspects were considered during the development and costly components, such as the x, y, and z linear axes, were minimized. Herein, a systems engineering approach for the development of a high-throughput MEW technology platform is presented for the first time.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherMary Ann Liebert, Inc.
dc.relation.ispartofpagefrom82
dc.relation.ispartofpageto90
dc.relation.ispartofissue2
dc.relation.ispartofjournal3D Printing and Additive Manufacturing
dc.relation.ispartofvolume6
dc.subject.fieldofresearchBiomedical Engineering
dc.subject.fieldofresearchMaterials Engineering
dc.subject.fieldofresearchcode0903
dc.subject.fieldofresearchcode0912
dc.subject.keywordsScience & Technology
dc.subject.keywordsTechnology
dc.subject.keywordsEngineering, Manufacturing
dc.subject.keywordsMaterials Science, Multidisciplinary
dc.subject.keywordsEngineering
dc.titleDesign and Development of a Three-Dimensional Printing High-Throughput Melt Electrowriting Technology Platform
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationWunner, FM; Eggert, S; Maartens, J; Bas, O; Dalton, PD; De-Juan-Pardo, EM; Hutmacher, DW, Design and Development of a Three-Dimensional Printing High-Throughput Melt Electrowriting Technology Platform, 3D Printing and Additive Manufacturing, 2019, 6 (2), pp. 82-90
dc.date.updated2019-09-10T00:47:24Z
gro.hasfulltextNo Full Text
gro.griffith.authorHutmacher, Dietmar W.


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