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dc.contributor.authorSalga, Marjorie
dc.contributor.authorTseng, Hsu-Wen
dc.contributor.authorAlexander, Kylie A
dc.contributor.authorJose, Beulah
dc.contributor.authorVaquette, Cedryck
dc.contributor.authorDebaud, Charlotte
dc.contributor.authorGatin, Laure
dc.contributor.authorGenet, Francois
dc.contributor.authorLevesque, Jean-Pierre
dc.date.accessioned2019-09-11T23:54:21Z
dc.date.available2019-09-11T23:54:21Z
dc.date.issued2019
dc.identifier.issn1877-0657
dc.identifier.doi10.1016/j.rehab.2019.01.005
dc.identifier.urihttp://hdl.handle.net/10072/387230
dc.description.abstractDear Editor, Neurogenic heterotopic ossifications (NHOs) are benign ectopic bones that develop within the muscle tissue surrounding extracapsular bone joints [1] after severe lesions of the central nervous system (CNS) such as spinal cord injury (SCI) or traumatic brain injury [2]. NHOs are often diagnosed late, thereby resulting in large ossifications causing joint pain and stiffness that often progress to partial or complete joint ankyloses. Complications such as nerve and blood vessel compression and skin bedsores occur further exacerbate patient morbidity. Occurrence of NHO delays recovery from injury, interrupts rehabilitation programs and lengthens the hospital stay [3]. There is no effective pharmacological treatment to reduce the burden of NHO. Surgical resection of troublesome NHO remains the only treatment and provides some benefit for mobility [3].
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom189
dc.relation.ispartofpageto192
dc.relation.ispartofissue3
dc.relation.ispartofjournalAnnals of Physical and Rehabilitation Medicine
dc.relation.ispartofvolume62
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsRehabilitation
dc.subject.keywordsNeurogenic heterotopic ossification
dc.subject.keywordsSpinal cord injury
dc.titleBlocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice
dc.typeJournal article
dc.type.descriptionC3 - Articles (Letter/ Note)
dcterms.bibliographicCitationSalga, M; Tseng, H-W; Alexander, KA; Jose, B; Vaquette, C; Debaud, C; Gatin, L; Genet, F; Levesque, J-P, Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice, Annals of Physical and Rehabilitation Medicine, 2019, 62 (3), pp. 189-192
dcterms.dateAccepted2019-01-06
dc.date.updated2019-09-11T23:51:47Z
gro.hasfulltextNo Full Text
gro.griffith.authorVaquette, Cedryck


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