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dc.contributor.authorDonkin, Rebecca
dc.contributor.authorDettrick, Andrew
dc.contributor.authorWyche, Penelope
dc.contributor.authorGrigg, Sarah
dc.date.accessioned2019-09-17T02:03:25Z
dc.date.available2019-09-17T02:03:25Z
dc.date.issued2018
dc.identifier.issn0031-3025
dc.identifier.doi10.1016/j.pathol.2018.06.003
dc.identifier.urihttp://hdl.handle.net/10072/387406
dc.description.abstractSir, Incidental findings of benign spindle-shaped cells with oval to indented spindle nuclei inclusions have been described predominantly in lung cancer cases and given the name minute pulmonary meningothelial-like nodules or MPMN.1, 2, 3 It was proposed by Gaffey et al. in 19881 that the morphological characteristics of a meningothelial-like nodule closely resemble meningothelial cells. This relationship has been supported by immunohistochemical (IHC) analysis which reveals the strong reactivity of MPMN to epithelial membrane antigen (EMA) and the filament protein vimentin. In contrast, other papers have reported ‘meningothelial-like whorls’ from tissue outside of the lung,2, 3, 4 describing positive staining for myosin, alpha smooth muscle actin (α-SMA) and negative for EMA, suggesting muscle origin. Due to the inconsistent IHC results, the origin of these benign inclusions is unclear. It is yet to be determined if anatomical location of the inclusion reflects the IHC profile. Herein, we report a unique case of benign meningothelial inclusions in cervical lymph nodes, which has not been reported previously to the authors' knowledge.
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom785
dc.relation.ispartofpageto787
dc.relation.ispartofissue7
dc.relation.ispartofjournalPathology
dc.relation.ispartofvolume50
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode1103
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsPathology
dc.subject.keywordsWHORLS
dc.subject.keywordsLIPOSARCOMA
dc.titleAtypical finding of meningothelial-like inclusions in cervical lymph nodes
dc.typeJournal article
dc.type.descriptionC3 - Articles (Letter/ Note)
dcterms.bibliographicCitationDonkin, R; Dettrick, A; Wyche, P; Grigg, S, Atypical finding of meningothelial-like inclusions in cervical lymph nodes, Pathology, 2018, 50 (7), pp. 785-787
dcterms.dateAccepted2018-06-06
dc.date.updated2019-09-17T02:00:58Z
gro.hasfulltextNo Full Text
gro.griffith.authorDettrick, Andrew J.


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