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dc.contributor.authorAgbor, Valirie Ndip
dc.contributor.authorTakah, Noah Fongwen
dc.contributor.authorAminde, Leopold Ndemnge
dc.date.accessioned2019-09-17T04:59:16Z
dc.date.available2019-09-17T04:59:16Z
dc.date.issued2018
dc.identifier.issn2044-6055
dc.identifier.doi10.1136/bmjopen-2017-020715
dc.identifier.urihttp://hdl.handle.net/10072/387437
dc.description.abstractIntroduction: Hypertension is the leading cardiovascular risk factor globally, associated with a high morbidity and mortality. The high prevalence of hypertension in sub-Saharan Africa (SSA) is associated with contrastingly low awareness, treatment and control rates. Adherence to medication remains a major determinant of optimal blood pressure control. This systematic review aims to determine the prevalence, and factors associated with adherence to antihypertensive pharmacotherapy among patients with hypertension in SSA. Methods and analysis: We will include studies published in Africa up to 31 December 2017. The following databases will be searched: PubMed, Embase, SCOPUS and Web of Science to identify potential studies without language restriction. To minimise chances of missing studies, resources specific to African literature such as WHO AFROLIB, African Index Medicus and African Journals Online will also be searched. Two reviewers will independently screen studies, extract data and critically appraise included studies for risk of bias, and a third reviewer will resolve discrepancies. A random-effects meta-analysis is planned to pool study-specific estimates to obtain a summary measure presented in Forest plots. Heterogeneity of included studies will be assessed using the χ2 test on Cochrane’s Q statistic and quantified using I2. Publication bias will be assessed using the Egger’s test and funnel plots. This protocol has been prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses for Protocols 2015 statement. Ethical and dissemination: An ethical approval is not required for the proposed study, as it will be based on already published data. The end report will be presented at conferences and published in a peer-reviewed journal. PROSPERO registration number: CRD42017079838.
dc.languageEnglish
dc.publisherBMJ Publishing
dc.relation.ispartofissue3
dc.relation.ispartofjournalBMJ Open
dc.relation.ispartofvolume8
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchOther Medical and Health Sciences
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1117
dc.subject.fieldofresearchcode1199
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsMedicine, General & Internal
dc.subject.keywordsGeneral & Internal Medicine
dc.subject.keywordsDISEASE
dc.titlePrevalence and factors associated with medication adherence among patients with hypertension in sub-Saharan Africa: protocol for a systematic review and meta-analysis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationAgbor, VN; Takah, NF; Aminde, LN, Prevalence and factors associated with medication adherence among patients with hypertension in sub-Saharan Africa: protocol for a systematic review and meta-analysis, BMJ Open, 2018, 8 (3)
dcterms.licensehttp://creativecommons.org/licenses/by-nc/4.0/
dc.date.updated2019-09-17T04:03:07Z
dc.description.versionPublished
gro.rights.copyright© The Author(s). 2018. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
gro.hasfulltextFull Text
gro.griffith.authorAminde, Leopold N.


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