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dc.contributor.authorAgbor, Valirie Ndip
dc.contributor.authorNjim, Tsi
dc.contributor.authorAminde, Leopold Ndemnge
dc.date.accessioned2019-09-18T01:03:04Z
dc.date.available2019-09-18T01:03:04Z
dc.date.issued2016
dc.identifier.issn1752-1947
dc.identifier.doi10.1186/s13256-016-1142-x
dc.identifier.urihttp://hdl.handle.net/10072/387457
dc.description.abstractBACKGROUND: Raynaud's phenomenon is a microvascular disorder that results in exaggerated vasoconstriction over vasodilatation secondary to an alteration in autonomic control. Though benign, it can result in severe ulceration and ultimately gangrene associated with disfiguration and permanent deformity. We present a case of severe secondary Raynaud's phenomenon in a black-African patient from a resource-limited setting, with focus on the difficulties encountered in the diagnosis and treatment. CASE PRESENTATION: A 43-year-old female Cameroonian farmer with a 7-year history of episodic paresthesia in her fingers and toes (when exposed to cold) presented to our emergency department with severe pain, ulceration, and "darkening" of her fingertips over a period of 2 days. An examination revealed bilateral ulceration and dry gangrene of her fingers and toes, based on which a diagnosis of secondary Raynaud's phenomenon due to a connective tissue disease was proposed. Results of paraclinical investigations were normal. Lifestyle modification along with a calcium channel blocker and phosphodiesterase type 5 inhibitor provided significant relief. CONCLUSIONS: An early diagnosis and knowledge on appropriate treatment of Raynaud's phenomenon is of vital importance to prevent permanent tissue damage and disability. Relying on biphasic color change for the diagnosis of Raynaud's phenomenon in black Africans can be potentially misleading.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer Nature
dc.relation.ispartofpagefrom356:1
dc.relation.ispartofpageto356:4
dc.relation.ispartofissue1
dc.relation.ispartofjournalJournal of Medical Case Reports
dc.relation.ispartofvolume10
dc.subject.fieldofresearchOther Medical and Health Sciences
dc.subject.fieldofresearchcode1199
dc.subject.keywordsCameroon
dc.subject.keywordsConnective tissue disease
dc.subject.keywordsSecondary Raynaud’s phenomenon
dc.titleDifficulties in diagnosis and treatment of severe secondary Raynaud's phenomenon in a Cameroonian woman: a case report
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationAgbor, VN; Njim, T; Aminde, LN, Difficulties in diagnosis and treatment of severe secondary Raynaud's phenomenon in a Cameroonian woman: a case report., Journal of Medical Case Reports, 2016, 10 (1), pp. 356-
dcterms.dateAccepted2016-11-09
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2019-09-17T04:24:16Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s). 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
gro.hasfulltextFull Text
gro.griffith.authorAminde, Leopold N.


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