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dc.contributor.authorKehbila, Jules
dc.contributor.authorEkabe, Cyril Jabea
dc.contributor.authorAminde, Leopold Ndemnge
dc.contributor.authorNoubiap, Jean Jacques N
dc.contributor.authorFon, Peter Nde
dc.contributor.authorMonekosso, Gottlieb Lobe
dc.date.accessioned2019-09-18T02:05:35Z
dc.date.available2019-09-18T02:05:35Z
dc.date.issued2016
dc.identifier.issn2095-5162
dc.identifier.doi10.1186/s40249-016-0145-6
dc.identifier.urihttp://hdl.handle.net/10072/387464
dc.description.abstractBACKGROUND: Tuberculosis (TB) remains a global health challenge and depression is a significant contributor to the global burden of disease. Current evidence suggests that there is an association between depressive symptoms and TB, lower adherence to treatment, and increased morbidity and mortality. However, there is paucity of data regarding these associations in Cameroon. This study aimed to determine the prevalence and correlates of depression in adult patients with pulmonary TB (PTB) in the Southwest Region of Cameroon. METHODS: A hospital-based cross-sectional study involving 265 patients with PTB was conducted from 2(nd) January to 31(st) March 2015 in the Limbe Regional Hospital and the Kumba District Hospital. Depression was diagnosed using the standard nine-item Patient Health Questionnaire, and classified as none, mild or moderate. Logistic regressions were used to investigate correlates of depression in these patients. RESULTS: Of the 265 patients (mean age 36.9 ± 10 years) studied, 136 (51.3 %) were female. The prevalence of depression was 61.1 % (95 % CI: 55.1-66.8), with a significant proportion (36.6 %) having mild depression. Multivariable logistic regression analysis showed that being female (aOR = 3.0, 95 % CI (1.7-5.5), P < 0.001), having a family history of mental illness (aOR = 2.5, 95 % CI: 1.3-5.4, P > 0.05), being on retreatment for TB (aOR = 11.2, 95 % CI: 5.2-31.1, P < 0.001), having discontinued treatment (aOR = 8.2, 95 % CI: 1.1-23.3, P < 0.05) and having a HIV/TB co-infection (aOR = 2.5, 95 % CI: 1.2-6.5, P < 0.001) were factors associated with having a higher chance of being depressed. CONCLUSION: Our study suggests that there is a high prevalence of depression among PTB patients, with more than one in two patients affected. Multidisciplinary care for TB patients involving mental health practitioners is highly encouraged, especially for high-risk groups.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBioMed Central Ltd.
dc.relation.ispartofpagefrom51:1
dc.relation.ispartofpageto51:8
dc.relation.ispartofissue1
dc.relation.ispartofjournalInfectious Diseases of Poverty
dc.relation.ispartofvolume5
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode1103
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsInfectious Diseases
dc.subject.keywordsPrevalence
dc.subject.keywordsCorrelates
dc.titlePrevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationKehbila, J; Ekabe, CJ; Aminde, LN; Noubiap, JJN; Fon, PN; Monekosso, GL, Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon, INFECTIOUS DISEASES OF POVERTY, 2016, 5 (1), pp. 51:1-51:8
dcterms.dateAccepted2016-05-10
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2019-09-17T04:30:31Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2016 Kehbila et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
gro.hasfulltextFull Text
gro.griffith.authorAminde, Leopold N.


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