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dc.contributor.authorAminde, Leopold Ndemnge
dc.contributor.authorDzudie, Anastase
dc.contributor.authorTakah, Noah Fongwen
dc.contributor.authorNgu, Kathleen Blackett
dc.contributor.authorSliwa, Karen
dc.contributor.authorKengne, Andre Pascal
dc.date.accessioned2019-09-18T04:56:08Z
dc.date.available2019-09-18T04:56:08Z
dc.date.issued2015
dc.identifier.issn2223-3652en_US
dc.identifier.doi10.3978/j.issn.2223-3652.2015.03.07en_US
dc.identifier.urihttp://hdl.handle.net/10072/387481
dc.description.abstractLutembacher syndrome (LS) is a rare cardiac abnormality characterized by any combination of a congenital or iatrogenic atrial septal defect (ASD) and a congenital or acquired mitral stenosis (MS). Clinical features and hemodynamic effects of LS depend on the balance of effects of the MS and the ASD. Prognosis is influenced by several factors [pulmonary vascular resistance, right ventricle (RV) compliance, size of ASD and MS severity] but the occurrence of secondary pulmonary hypertension and congestive heart failure is commonly associated with poor outcome. Echocardiography remains the gold standard for diagnosis and evaluation of LS. Timely diagnosis is critical for modifying the natural course, by allowing patients to benefit from currently available percutaneous trans-catheter therapies with favorable effects on the outcomes. This article is a review of published literature on the current diagnostic and therapeutic modalities for LS, focusing on the pivotal role of echocardiography as the key diagnostic tool. Clinical suspicion of LS should prompt extensive investigation with non-invasive and where possible, invasive technics. Multicenter registers have a potential to assist the evaluation of long term outcomes of percutaneous trans-catheter therapies in patients with LS.en_US
dc.languageEnglishen_US
dc.language.isoeng
dc.publisherAME Publishing Companyen_US
dc.relation.ispartofpagefrom122en_US
dc.relation.ispartofpageto132en_US
dc.relation.ispartofissue2en_US
dc.relation.ispartofjournalCardiovascular Diagnosis and Therapyen_US
dc.relation.ispartofvolume5en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsCardiac & Cardiovascular Systemsen_US
dc.subject.keywordsCardiovascular System & Cardiologyen_US
dc.subject.keywordsLutembacher syndrome (LS)en_US
dc.titleCurrent diagnostic and treatment strategies for Lutembacher syndrome: the pivotal role of echocardiographyen_US
dc.typeJournal articleen_US
dcterms.bibliographicCitationAminde, LN; Dzudie, A; Takah, NF; Ngu, KB; Sliwa, K; Kengne, AP, Current diagnostic and treatment strategies for Lutembacher syndrome: the pivotal role of echocardiography, Cardiovascular Diagnosis and Therapy, 2015, 5 (2), pp. 122-132en_US
dcterms.dateAccepted2015-02-12
dc.date.updated2019-09-17T04:33:14Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyright© 2015 AME Publishing Company. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.en_US
gro.hasfulltextFull Text
gro.griffith.authorAminde, Leopold N.


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