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dc.contributor.authorKumar, A
dc.contributor.authorAnstey, C
dc.contributor.authorTesar, P
dc.contributor.authorShekar, K
dc.date.accessioned2019-09-20T00:52:59Z
dc.date.available2019-09-20T00:52:59Z
dc.date.issued2019
dc.identifier.issn0003-4975
dc.identifier.doi10.1016/j.athoracsur.2019.05.029
dc.identifier.urihttp://hdl.handle.net/10072/387551
dc.description.abstractBackground: This study aimed to identify risk factors associated with mortality of patients who undergo cardiac surgery for infective endocarditis. Methods: A retrospective review was performed of patients with infective endocarditis who underwent cardiac surgery at a quaternary Australian hospital between 2004 and 2014. Patient data were collected and prospectively analyzed. Results: In all, 465 patients underwent surgery during the study period, with 30 deaths (6.45%). Factors independently associated with in-hospital mortality were increasing age (odds ratio [OR] 1.04; 95% confidence interval [CI], 1.01 to 1.07; P = .009), active bacterial endocarditis at time of operation (OR 4.91; 95% CI, 1.01 to 23.8; P = .048), preoperative invasive positive pressure ventilation (OR 3.65; 95% CI, 1.18 to 11.27; P = .025), increasing cardiopulmonary bypass time (OR 1.01; 95% CI, 1.006 to 1.014; P < .001), and increasing European System for Cardiac Operative Risk Evaluation score (OR 21.73; 95% CI, 2.12 to 223.11; P < .01). Conclusions: The in-hospital mortality of patients with infective endocarditis remains significant, with potential risk factors including increasing age, active bacterial endocarditis, preoperative invasive positive pressure ventilation, increasing cardiopulmonary bypass time, and high European System for Cardiac Operative Risk Evaluation score.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited States
dc.relation.ispartofpagefrom1101
dc.relation.ispartofpageto1106
dc.relation.ispartofissue4
dc.relation.ispartofjournalAnnals of Thoracic Surgery
dc.relation.ispartofvolume108
dc.subject.fieldofresearchCardiorespiratory Medicine and Haematology
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode1102
dc.subject.fieldofresearchcode1103
dc.titleRisk Factors for Mortality in Patients Undergoing Cardiothoracic Surgery for Infective Endocarditis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationKumar, A; Anstey, C; Tesar, P; Shekar, K, Risk Factors for Mortality in Patients Undergoing Cardiothoracic Surgery for Infective Endocarditis, Annals of Thoracic Surgery, 2019, 108 (4), pp. 1101-1106
dcterms.dateAccepted2019-05-06
dc.date.updated2019-09-20T00:11:14Z
gro.hasfulltextNo Full Text
gro.griffith.authorAnstey, Christopher


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