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dc.contributor.authorFranklin, D
dc.contributor.authorFraser, JF
dc.contributor.authorSchibler, A
dc.date.accessioned2019-09-23T03:40:40Z
dc.date.available2019-09-23T03:40:40Z
dc.date.issued2019
dc.identifier.issn1526-0542
dc.identifier.doi10.1016/j.prrv.2018.10.001
dc.identifier.urihttp://hdl.handle.net/10072/387642
dc.description.abstractBronchiolitis is a common viral disease that significantly affects infants less than 12 months of age. The purpose of this review is to present a review of the current knowledge of the uses of respiratory support in the management of infants with bronchiolitis presenting to hospital. We electronically searched MEDLINE, Cochrane, CINAHL and EMBASE (inception to 25th March 2018), to manually search for clinical trials that address the management strategies for respiratory support of infants with bronchiolitis. We identified 120 papers who met the inclusion criteria, of which 33 papers were relevant for this review with only nine randomized controlled trials. This review demonstrated that non-invasive respiratory support reduced the need for escalation of therapy, particularly the proportion of intubations required for infants with bronchiolitis. Additionally, clear economic benefits have been demonstrated when non-invasive ventilation has been used. The potential early use of non-invasive respiratory supports such as nasal high flow therapy and non-invasive ventilation may have an impact on health care costs and reduction in ICU admissions and intubation rates. High-grade evidence demonstrates safety and quality of high flow therapy in general ward settings.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom16
dc.relation.ispartofpageto24
dc.relation.ispartofjournalPaediatric Respiratory Reviews
dc.relation.ispartofvolume30
dc.subject.fieldofresearchCardiovascular medicine and haematology
dc.subject.fieldofresearchcode3201
dc.subject.keywordsBronchiolitis
dc.subject.keywordsInfant
dc.subject.keywordsInvasive mechanical ventilation
dc.subject.keywordsNasal high flow
dc.subject.keywordsNon-invasive ventilation
dc.titleRespiratory support for infants with bronchiolitis, a narrative review of the literature
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationFranklin, D; Fraser, JF; Schibler, A, Respiratory support for infants with bronchiolitis, a narrative review of the literature, Paediatric Respiratory Reviews, 2019, 30, pp. 16-24
dcterms.dateAccepted2018-10-04
dc.date.updated2019-09-23T03:38:47Z
gro.hasfulltextNo Full Text
gro.griffith.authorFraser, John F.


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