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dc.contributor.authorFranklin, D
dc.contributor.authorFraser, JF
dc.contributor.authorSchibler, A
dc.description.abstractBronchiolitis is a common viral disease that significantly affects infants less than 12 months of age. The purpose of this review is to present a review of the current knowledge of the uses of respiratory support in the management of infants with bronchiolitis presenting to hospital. We electronically searched MEDLINE, Cochrane, CINAHL and EMBASE (inception to 25th March 2018), to manually search for clinical trials that address the management strategies for respiratory support of infants with bronchiolitis. We identified 120 papers who met the inclusion criteria, of which 33 papers were relevant for this review with only nine randomized controlled trials. This review demonstrated that non-invasive respiratory support reduced the need for escalation of therapy, particularly the proportion of intubations required for infants with bronchiolitis. Additionally, clear economic benefits have been demonstrated when non-invasive ventilation has been used. The potential early use of non-invasive respiratory supports such as nasal high flow therapy and non-invasive ventilation may have an impact on health care costs and reduction in ICU admissions and intubation rates. High-grade evidence demonstrates safety and quality of high flow therapy in general ward settings.en_US
dc.publisherElsevier BVen_US
dc.relation.ispartofjournalPaediatric Respiratory Reviewsen_US
dc.subject.fieldofresearchCardiorespiratory Medicine and Haematologyen_US
dc.subject.keywordsInvasive mechanical ventilationen_US
dc.subject.keywordsNasal high flowen_US
dc.subject.keywordsNon-invasive ventilationen_US
dc.titleRespiratory support for infants with bronchiolitis, a narrative review of the literatureen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationFranklin, D; Fraser, JF; Schibler, A, Respiratory support for infants with bronchiolitis, a narrative review of the literature, Paediatric Respiratory Reviews, 2019, 30, pp. 16-24en_US
gro.hasfulltextNo Full Text
gro.griffith.authorFraser, John F.

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