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dc.contributor.authorGong, J
dc.contributor.authorWang, Y
dc.contributor.authorLiu, J
dc.contributor.authorFu, X
dc.contributor.authorCheung, EFC
dc.contributor.authorChan, RCK
dc.date.accessioned2019-09-23T03:54:44Z
dc.date.available2019-09-23T03:54:44Z
dc.date.issued2019
dc.identifier.issn0165-1781
dc.identifier.doi10.1016/j.psychres.2019.02.064
dc.identifier.urihttp://hdl.handle.net/10072/387647
dc.description.abstractThis study aimed to measure the associations between high sensitivity C-reactive protein (hsCRP), childhood maltreatment (CM), schizotypy and response inhibition, and to explore the interactions between hsCRP, CM and schizotypy on response inhibition. Two hundred and fourteen participants completed the Stop-Signal Task (SST), the Schizotypy Personality Questionnaire (SPQ) and the Childhood Trauma Questionnaire-Short Form (CTQ), which measured response inhibition, schizotypy and history of CM respectively. The level of hsCRP was also measured. The high schizotypy group (n = 114) had higher scores on SPQ and CTQ, higher hsCRP levels and longer SST reaction times (SSRTs) than the low schizotypy group (n = 100). In female participants, SSRT had a positive correlation with the SPQ positive factor and the disorganized SPQ factor and a positive correlation with physical neglect. HsCRP was positively correlated with the SPQ negative factor and positive SPQ factor. In male participants, SSRT was negatively correlated with emotional neglect and physical neglect. The majority of correlations between CTQ and SPQ variables were significant in both female and male participants. In female participants, hsCRP significantly predicted SSRT, and hsCRP significantly interacted with positive schizotypy in predicting SSRT.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom365
dc.relation.ispartofpageto371
dc.relation.ispartofjournalPsychiatry Research
dc.relation.ispartofvolume274
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode52
dc.subject.keywordsChildhood maltreatment
dc.subject.keywordsHigh sensitive C-reactive protein
dc.subject.keywordsResponse inhibition
dc.subject.keywordsSchizotypy
dc.titleThe interaction between positive schizotypy and high sensitivity C-reactive protein on response inhibition in female individuals
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationGong, J; Wang, Y; Liu, J; Fu, X; Cheung, EFC; Chan, RCK, The interaction between positive schizotypy and high sensitivity C-reactive protein on response inhibition in female individuals, Psychiatry Research, 2019, 274, pp. 365-371
dcterms.dateAccepted2019-02-25
dc.date.updated2019-09-23T03:53:15Z
gro.hasfulltextNo Full Text
gro.griffith.authorChan, Raymond


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