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  • Developing a cerebral palsy-specific preference-based measure for a six-dimensional classification system (CP-6D): protocol for a valuation study

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    Version of Record (VoR)
    Author(s)
    Bahrampour, M
    Norman, R
    Byrnes, J
    Downes, M
    Scuffham, PA
    Griffith University Author(s)
    Scuffham, Paul A.
    Byrnes, Joshua M.
    Downes, Martin J.
    Year published
    2019
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    Abstract
    Introduction: Cerebral palsy (CP) is a lifelong condition. The CP quality of life (CPQOL) instrument is a frequently used disease-specific instrument to assess health-related quality of life (HRQoL) in people with CP, but it cannot be used to generate quality-adjusted life years (QALY) which are the basis of cost utility analysis (CUA). Generic utility instruments (such as the EQ-5D or SF-6D) that are used to value HRQOL may be insensitive to small but important health changes in children with CP. This study aims to generate a preference-based scoring algorithm for the CP six dimensions (CP-6D), a classification system ...
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    Introduction: Cerebral palsy (CP) is a lifelong condition. The CP quality of life (CPQOL) instrument is a frequently used disease-specific instrument to assess health-related quality of life (HRQoL) in people with CP, but it cannot be used to generate quality-adjusted life years (QALY) which are the basis of cost utility analysis (CUA). Generic utility instruments (such as the EQ-5D or SF-6D) that are used to value HRQOL may be insensitive to small but important health changes in children with CP. This study aims to generate a preference-based scoring algorithm for the CP six dimensions (CP-6D), a classification system developed from the CPQOL. Methods and analysis: A discrete choice experiment with duration (DCEtto) will be administrated to value health states described by the CP-6D classification system. These health states will be presented to members of Australian general population and parents of children with CP via an online survey. Conditional logit regression will be used to produce the utility algorithm for CP-6D. Ethics and dissemination: The Griffith University Human Research Ethics Committee approved for the study (reference HREC/number 2018/913). The developed algorithm can be applied to previous and future economic evaluation of interventions and treatments targeting people with CP which have used either the CPQOL or CP-6D.
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    Journal Title
    BMJ open
    Volume
    9
    Issue
    9
    DOI
    https://doi.org/10.1136/bmjopen-2019-029325
    Copyright Statement
    © Author(s) 2019. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.
    Subject
    Health economics
    Biomedical and clinical sciences
    Health sciences
    Psychology
    Cerebral palsy
    Choice experiment
    Preference
    health related utility values
    Publication URI
    http://hdl.handle.net/10072/387774
    Collection
    • Journal articles

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