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dc.contributor.authorSaglimbene, VM
dc.contributor.authorWong, G
dc.contributor.authorTeixeira-Pinto, A
dc.contributor.authorRuospo, M
dc.contributor.authorGarcia-Larsen, V
dc.contributor.authorPalmer, SC
dc.contributor.authorNatale, P
dc.contributor.authorCampbell, K
dc.contributor.authorCarrero, JJ
dc.contributor.authorStenvinkel, P
dc.contributor.authorGargano, L
dc.contributor.authorMurgo, AM
dc.contributor.authorJohnson, DW
dc.contributor.authorTonelli, M
dc.contributor.authoret al.
dc.date.accessioned2019-10-03T04:01:22Z
dc.date.available2019-10-03T04:01:22Z
dc.date.issued2019
dc.identifier.issn0272-6386en_US
dc.identifier.doi10.1053/j.ajkd.2019.05.028en_US
dc.identifier.urihttp://hdl.handle.net/10072/388032
dc.description.abstractRationale & Objective: Clinical practice guidelines for dietary intake in hemodialysis focus on individual nutrients. Little is known about associations of dietary patterns with survival. We evaluated the associations of dietary patterns with cardiovascular and all-cause mortality among adults treated by hemodialysis. Study Design: Prospective cohort study. Setting & Participants: 8,110 of 9,757 consecutive adults on hemodialysis (January 2014 to June 2017) treated in a multinational private dialysis network and with analyzable dietary data. Exposures: Data-driven dietary patterns based on the GA2LEN food frequency questionnaire. Participants received a score for each identified pattern, with higher scores indicating closer resemblance of their diet to the identified pattern. Quartiles of standardized pattern scores were used as primary exposures. Outcomes: Cardiovascular and all-cause mortality. Analytical Approach: Principal components analysis with varimax rotation to identify common dietary patterns. Adjusted proportional hazards regression analyses with country as a random effect to estimate the associations between dietary pattern scores and mortality. Associations were expressed as adjusted HRs with 95% CIs, using the lowest quartile score as reference. Results: During a median follow-up of 2.7 years (18,666 person-years), there were 2,087 deaths (958 cardiovascular). 2 dietary patterns, “fruit and vegetable” and “Western,” were identified. For the fruit and vegetable dietary pattern score, adjusted HRs, in ascending quartiles, were 0.94 (95% CI, 0.76-1.15), 0.83 (95% CI, 0.66-1.06), and 0.91 (95% CI, 0.69-1.21) for cardiovascular mortality and 0.95 (95% CI, 0.83-1.09), 0.84 (95% CI, 0.71-0.99), and 0.87 (95% CI, 0.72-1.05) for all-cause mortality. For the Western dietary pattern score, the corresponding estimates were 1.10 (95% CI, 0.90-1.35), 1.11 (95% CI, 0.87-1.41), and 1.09 (95% CI, 0.80-1.49) for cardiovascular mortality and 1.01 (95% CI, 0.88-1.16), 1.00 (95% CI, 0.85-1.18), and 1.14 (95% CI, 0.93-1.41) for all-cause mortality. Limitations: Self-reported food frequency questionnaire, data-driven approach. Conclusions: These findings did not confirm an association between mortality among patients receiving long-term hemodialysis and the extent to which dietary patterns were either high in fruit and vegetables or consistent with a Western diet.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherElsevieren_US
dc.publisher.placeUnited States
dc.relation.ispartofjournalAmerican Journal of Kidney Diseasesen_US
dc.subject.fieldofresearchClinical Sciencesen_US
dc.subject.fieldofresearchcode1103en_US
dc.titleDietary Patterns and Mortality in a Multinational Cohort of Adults Receiving Hemodialysisen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationSaglimbene, et al., Dietary Patterns and Mortality in a Multinational Cohort of Adults Receiving Hemodialysis, American Journal of Kidney Diseases, 2019en_US
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.date.updated2019-10-03T00:47:20Z
dc.description.versionPost-printen_US
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.en_US
gro.rights.copyright© 2019 The National Kidney Foundation Inc. Published by Elsevier Ltd. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.en_US
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gro.griffith.authorCampbell, Katrina


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