Encapsulation of live cells by metal-organic frameworks for viability protection
Author(s)
Sun, Chao
Chang, Lin
Hou, Ke
Liu, Shaoqin
Tang, Zhiyong
Griffith University Author(s)
Year published
2019
Metadata
Show full item recordAbstract
In this study, a yeast@ZIF-8 core–shell composite material was successfully synthesized under room temperature in aqueous solution. The ZIF-8 shell endowed the inner yeast cells with a considerably extended lifetime without any nutrients at 4°C. Compared with the bare yeast cells, most coated yeast cells were kept alive even when cultured in zymolyase solution for 3 h. Furthermore, the encapsulated yeast cells could be reactivated and regrown by dissolving the ZIF-8 shell with competitive coordination interactions.In this study, a yeast@ZIF-8 core–shell composite material was successfully synthesized under room temperature in aqueous solution. The ZIF-8 shell endowed the inner yeast cells with a considerably extended lifetime without any nutrients at 4°C. Compared with the bare yeast cells, most coated yeast cells were kept alive even when cultured in zymolyase solution for 3 h. Furthermore, the encapsulated yeast cells could be reactivated and regrown by dissolving the ZIF-8 shell with competitive coordination interactions.
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Journal Title
Science China Materials
Volume
62
Issue
6
Subject
Nanotechnology
Nanomaterials
Inorganic materials (incl. nanomaterials)
Science & Technology
Technology
Materials Science, Multidisciplinary
Materials Science
live cells