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dc.contributor.authorYaxley, Julian
dc.date.accessioned2019-10-15T01:23:13Z
dc.date.available2019-10-15T01:23:13Z
dc.date.issued2016
dc.identifier.issn2005-6443
dc.identifier.doi10.4082/kjfm.2016.37.6.310
dc.identifier.urihttp://hdl.handle.net/10072/388402
dc.description.abstractAn association between non-opioid analgesic agents and chronic kidney disease has long been suspected. The presumed development of chronic renal impairment following protracted and excessive use of non-opioid analgesia is known as analgesic nephropathy. Many clinicians accept analgesic nephropathy as a real entity despite the paucity of scientific evidence. This narrative review aims to summarize the literature in the field. The weight of available observational literature suggests that long-term ingestion of paracetamol and combination mixtures of aspirin and paracetamol are likely to contribute to chronic renal impairment. However, there is no convincing data to implicate non-steroidal anti-inflammatory drugs or aspirin monotherapy in the development of analgesic nephropathy. In the absence of high-level evidence, while controversy persists, it may be prudent for physicians to consider all non-narcotic analgesics to be nephrotoxic with long-term use.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherKorean Academy of Family Medine
dc.publisher.placeRepublic of Korea
dc.relation.ispartofpagefrom310
dc.relation.ispartofpageto316
dc.relation.ispartofissue6
dc.relation.ispartofjournalKorean Journal of Family Medicine
dc.relation.ispartofvolume37
dc.subject.fieldofresearchHealth services and systems
dc.subject.fieldofresearchPublic health
dc.subject.fieldofresearchcode4203
dc.subject.fieldofresearchcode4206
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsPrimary Health Care
dc.subject.keywordsGeneral & Internal Medicine
dc.subject.keywordsNephropathy
dc.titleCommon Analgesic Agents and Their Roles in Analgesic Nephropathy: A Commentary on the Evidence
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationYaxley, J, Common Analgesic Agents and Their Roles in Analgesic Nephropathy: A Commentary on the Evidence, Korean Journal of Family Medicine, 2016, 37 (6), pp. 310-316
dcterms.dateAccepted2016-08-24
dcterms.licensehttps://creativecommons.org/licenses/by-nc/4.0/
dc.date.updated2019-10-15T00:44:59Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2016 The Korean Academy of Family Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorYaxley, Julian P.


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