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dc.contributor.authorVaradi, Linda
dc.contributor.authorBreedon, Michael
dc.contributor.authorChen, Fiona F
dc.contributor.authorTrinchi, Adrian
dc.contributor.authorCole, Ivan S
dc.contributor.authorWei, Gang
dc.date.accessioned2019-10-15T04:52:18Z
dc.date.available2019-10-15T04:52:18Z
dc.date.issued2019
dc.identifier.issn2046-2069
dc.identifier.doi10.1039/c8ra07656a
dc.identifier.urihttp://hdl.handle.net/10072/388407
dc.description.abstractThe Griess reaction is the most often exploited colorimetric method for the quantitative analysis of nitrite in aqueous media. The application of the currently used reagents are associated with limitations (e.g. linear response range). Herein, molecular fingerprint searching on well-known Griess-reagents was used as a tool for the identification of structurally similar, new reagent candidate molecules. Rapid and high-throughput experimental evaluation of the newly identified Griess-reagent candidates revealed that 14 of the 18 tested reagent candidates had equal or superior response displaying broader linear ranges and/or increased response gradient against various nitrite concentrations in aqueous media when compared to the parent compounds at room temperature.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherRoyal Society of Chemistry
dc.relation.ispartofpagefrom3994
dc.relation.ispartofpageto4000
dc.relation.ispartofissue7
dc.relation.ispartofjournalRSC Advances
dc.relation.ispartofvolume9
dc.subject.fieldofresearchChemical Sciences
dc.subject.fieldofresearchcode03
dc.subject.keywordsScience & Technology
dc.subject.keywordsPhysical Sciences
dc.subject.keywordsChemistry, Multidisciplinary
dc.subject.keywordsChemistry
dc.subject.keywordsNITRATE
dc.titleEvaluation of novel Griess-reagent candidates for nitrite sensing in aqueous media identified via molecular fingerprint searching
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationVaradi, L; Breedon, M; Chen, FF; Trinchi, A; Cole, IS; Wei, G, Evaluation of novel Griess-reagent candidates for nitrite sensing in aqueous media identified via molecular fingerprint searching, RSC Advances, 2019, 9 (7), pp. 3994-4000
dcterms.licensehttps://creativecommons.org/licenses/by-nc/3.0/
dc.date.updated2019-10-15T04:46:55Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s) 2019. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) License, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorCole, Ivan


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