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dc.contributor.authorChakradeo, Katrina
dc.contributor.authorBuzacott, Katie
dc.contributor.authorSoden, Muriel
dc.description.abstractA 57-year-old man presented for review in the rheumatology outpatients clinic. He had a 30-year history of rheumatoid arthritis and was known to be positive for rheumatoid factor and anticitrullinated protein antibodies (anti-CCP antibodies). He had been treated over the past 30 years with various immunosuppression regimens, including long-term methotrexate, leflunomide and sulfasalazine. His disease had been stable for the past 2 years with no recent increase in nodules or episodes of acute synovitis. Several times in the past 15 years his diagnosis of rheumatoid arthritis had come into question due to the atypical appearance of his hands which closely resembled gout (figures 1 and 2). On two occasions, excision of rheumatoid nodules was sent for histology to exclude other diagnoses such as gout and multicentric reticulohistiocytosis. In both specimens, there was no evidence of birefringent urate crystals when exposed to polarised light. While reticulohistiocytosis also shows a proliferation of histiocytes, they are typically nodular and scattered. The characteristic pattern of pallisading histiocytes was consistent with rheumatoid nodules (figure 3).
dc.publisherBMJ Publishing Group Ltd
dc.publisher.placeUnited Kingdom
dc.relation.ispartofjournalBMJ Case Reports
dc.subject.fieldofresearchClinical Sciences
dc.titleNodular rheumatoid arthritis resembling gout
dc.typeJournal article
dc.type.descriptionC2 - Articles (Other)
dcterms.bibliographicCitationChakradeo, K; Buzacott, K; Soden, M, Nodular rheumatoid arthritis resembling gout, BMJ Case Reports, 2016, 2016, pp. 1-2
gro.hasfulltextNo Full Text
gro.griffith.authorChakradeo, Katrina K.

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