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  • Nanoemulsions in drug delivery: formulation to medical application

    Author(s)
    Tayeb, Hossam H
    Sainsbury, Frank
    Griffith University Author(s)
    Sainsbury, Frank
    Year published
    2018
    Metadata
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    Abstract
    Nanoscale oil-in-water emulsions (NEs), heterogeneous systems of two immiscible liquids stabilized by emulsifiers or surfactants, show great potential in medical applications because of their attractive characteristics for drug delivery. NEs have been explored as therapeutic carriers for hydrophobic compounds via various routes of administration. NEs provide opportunities to improve drug delivery via alternative administration routes. However, deep understanding of the NE manufacturing and functionalization fundamentals, and how they relate to the choice of administration route and pharmacological profile is still needed to ...
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    Nanoscale oil-in-water emulsions (NEs), heterogeneous systems of two immiscible liquids stabilized by emulsifiers or surfactants, show great potential in medical applications because of their attractive characteristics for drug delivery. NEs have been explored as therapeutic carriers for hydrophobic compounds via various routes of administration. NEs provide opportunities to improve drug delivery via alternative administration routes. However, deep understanding of the NE manufacturing and functionalization fundamentals, and how they relate to the choice of administration route and pharmacological profile is still needed to ease the clinical translation of NEs. Here, we review the diversity of medical applications for NEs and how that governs their formulation, route of administration, and the emergence of increasing sophistication in NE design for specific application.
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    Journal Title
    Nanomedicine
    Volume
    13
    Issue
    19
    DOI
    https://doi.org/10.2217/nnm-2018-0088
    Subject
    Physical chemistry
    Medical biotechnology
    Nanotechnology
    Science & Technology
    Life Sciences & Biomedicine
    Biotechnology & Applied Microbiology
    Nanoscience & Nanotechnology
    Science & Technology - Other Topics
    Publication URI
    http://hdl.handle.net/10072/388498
    Collection
    • Journal articles

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