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dc.contributor.authorBach, KE
dc.contributor.authorKelly, JT
dc.contributor.authorPalmer, SC
dc.contributor.authorKhalesi, S
dc.contributor.authorStrippoli, GFM
dc.contributor.authorCampbell, KL
dc.date.accessioned2019-10-17T23:22:30Z
dc.date.available2019-10-17T23:22:30Z
dc.date.issued2019
dc.identifier.issn1555-9041
dc.identifier.doi10.2215/CJN.00530119
dc.identifier.urihttp://hdl.handle.net/10072/388506
dc.description.abstractBackground and objectives: Whether a healthy dietary pattern may prevent the incidence of developing CKD is unknown. This study evaluated the associations between dietary patterns and the incidence of CKD in adults and children. Design, setting, participants, & measurements: This systematic review and meta-analysis identified potential studies through a systematic search of MEDLINE, Embase and references from eligible studies from database inception to February 2019. Eligible studies were prospective and retrospective cohort studies including adults and children without CKD, where the primary exposure was dietary patterns. To be eligible, studies had to report on the primary outcome, incidence of CKD (eGFR<60 ml/min per 1.73 m2). Two authors independently extracted data, assessed risk of bias and evidence certainty using the Newcastle–Ottawa scale and GRADE. Results: Eighteen prospective cohort studies involving 630,108 adults (no children) with a mean follow-up of 10.4±7.4 years were eligible for analysis. Included studies had an overall low risk of bias. The evidence certainty was moderate for CKD incidence and low for eGFR decline (percentage drop from baseline or reduced by at least 3 ml/min per 1.73 m2 per year) and incident albuminuria. Healthy dietary patterns typically encouraged higher intakes of vegetables, fruit, legumes, nuts, whole grains, fish and low-fat dairy, and lower intakes of red and processed meats, sodium, and sugar-sweetened beverages. A healthy dietary pattern was associated with a lower incidence of CKD (odds ratio [OR] 0.70 (95% confidence interval [95% CI], 0.60 to 0.82); I2=51%; eight studies), and incidence of albuminuria (OR 0.77, [95% CI, 0.59 to 0.99]; I2=37%); four studies). There appeared to be no significant association between healthy dietary patterns and eGFR decline (OR 0.70 [95% CI, 0.49 to 1.01], I2=49%; four studies).
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Society of Nephrology
dc.publisher.placeUnited States
dc.relation.ispartofpagefrom1441
dc.relation.ispartofpageto1449
dc.relation.ispartofissue10
dc.relation.ispartofjournalClinical journal of the American Society of Nephrology
dc.relation.ispartofvolume14
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode1103
dc.subject.keywordsDASH
dc.subject.keywordsDiet
dc.subject.keywordsMediterranean
dc.subject.keywordsadult
dc.subject.keywordsalbuminuria
dc.titleHealthy Dietary Patterns and Incidence of CKD: A Meta-Analysis of Cohort Studies
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationBach, KE; Kelly, JT; Palmer, SC; Khalesi, S; Strippoli, GFM; Campbell, KL, Healthy Dietary Patterns and Incidence of CKD: A Meta-Analysis of Cohort Studies, Clinical journal of the American Society of Nephrology, 2019, 14 (10), pp. 1441-1449
dcterms.dateAccepted2019-07-05
dc.date.updated2019-10-17T06:11:16Z
gro.hasfulltextNo Full Text
gro.griffith.authorCampbell, Katrina
gro.griffith.authorKelly, Jaimon


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