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dc.contributor.authorHeffernan, A
dc.contributor.authorLipman, J
dc.contributor.authorRoberts, J
dc.date.accessioned2019-12-02T03:38:19Z
dc.date.available2019-12-02T03:38:19Z
dc.date.issued2018
dc.identifier.issn1198-743Xen_US
dc.identifier.doi10.1016/j.cmi.2017.12.019en_US
dc.identifier.urihttp://hdl.handle.net/10072/389430
dc.description.abstractDear Sir, We read with interest the comments from Ong et al. [1] regarding the need for a well-designed randomized controlled trial (RCT) to provide evidence to guide clinicians regarding the use of combined β-lactam antibiotic and aminoglycoside therapy for the management of critically ill patients with sepsis or septic shock. We would like to highlight the importance of appropriate dosing strategies and the inclusion of pharmacokinetic/pharmacodynamic (PK/PD) sub-studies to provide further evidence about the potential utility of combination therapy.en_US
dc.languageEnglishen_US
dc.publisherElsevieren_US
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefrom666en_US
dc.relation.ispartofpageto667en_US
dc.relation.ispartofissue6en_US
dc.relation.ispartofjournalClinical Microbiology and Infectionen_US
dc.relation.ispartofvolume24en_US
dc.subject.fieldofresearchClinical Sciencesen_US
dc.subject.fieldofresearchcode1103en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsInfectious Diseasesen_US
dc.subject.keywordsMicrobiologyen_US
dc.subject.keywordsNOSOCOMIAL PNEUMONIAen_US
dc.titleRe: 'Is a randomized trial of a short course of aminoglycoside added to beta-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified?' Pharmacokinetic/pharmacodynamic considerationsen_US
dc.typeJournal articleen_US
dc.type.descriptionC2 - Articles (Other)en_US
dcterms.bibliographicCitationHeffernan, A; Lipman, J; Roberts, J, Re: 'Is a randomized trial of a short course of aminoglycoside added to beta-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified?' Pharmacokinetic/pharmacodynamic considerations, Clinical Microbiology and Infection, 2018, 24 (6), pp. 666-667en_US
dcterms.dateAccepted2017-12-21
dc.date.updated2019-12-02T01:05:19Z
gro.hasfulltextNo Full Text
gro.griffith.authorHeffernan, Aaron J.


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