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dc.contributor.authorMercado, Faustino
dc.contributor.authorHamlet, Stephen
dc.contributor.authorIvanovski, Sašo
dc.date.accessioned2019-12-11T02:33:30Z
dc.date.available2019-12-11T02:33:30Z
dc.date.issued2019
dc.identifier.issn0022-3484
dc.identifier.doi10.1111/jre.12715
dc.identifier.urihttp://hdl.handle.net/10072/389654
dc.description.abstractBACKGROUND AND OBJECTIVE: The study compared clinical and patient-centered outcomes of subepithelial connective tissue graft (CTG) with and without enamel matrix derivative (EMD) in the treatment of Class I-II Miller periodontal recession defects. MATERIAL AND METHODS: This prospective clinical study evaluated 80 patients over a 3 years follow-up in a private periodontal practice. A total of 144 maxillary and mandibular anterior teeth were divided into two groups: group 1 (CTG with EMD-80 teeth) and group 2 (CTG only-64 teeth). Recession (REC), keratinized tissue (KT) width, % root overage, patient-centered outcomes, and pain visual analog scale (P-VAS) were compared between the two groups. RESULTS: At 3 years follow-up at a patient level, statistically significant changes in REC were achieved in both group 1 (4.65 ± 1.84 to 0.39 ± 0.19 mm) and group 2 (4.43 ± 1.11 to 0.92 ± 0.43 mm). Complete root coverage (CRC) was achieved in 66.4% of group 1 and 50.1% of group 2. At both patient and tooth level, the 3-year outcomes were superior for group 1 compared with group 2 in terms of % root coverage, REC, and KT width. Clinical attachment loss (CAL) was reduced in group 1 compared with group 2 at the tooth level analysis only (<.01). Significantly less pain was reported using the pain visual analog Scale (P < .001) at the two weeks follow-up post-surgery in group 1. CONCLUSIONS: Addition of EMD results in improved root coverage outcomes and higher amounts of keratinized tissue width 36 months after treatment of multiple adjacent recessions on maxillary and mandibular anterior teeth. The adjunctive use of EMD also resulted in significantly reduced pain 14 days after the surgery.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherWiley
dc.publisher.placeUnited States
dc.relation.ispartofjournalJournal of Periodontal Research
dc.relation.urihttp://purl.org/au-research/grants/NHMRC/APP1039946
dc.relation.grantIDAPP1039946
dc.relation.fundersNHMRC
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3203
dc.subject.keywordsenamel matrix proteins
dc.subject.keywordsgingival recession
dc.subject.keywordspain level
dc.subject.keywordsperiodontal plastic surgical flaps
dc.titleA 3‐year prospective clinical and patient‐centered trial on subepithelial connective tissue graft with or without enamel matrix derivative in Class I‐II Miller recessions
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationMercado, F; Hamlet, S; Ivanovski, S, A 3-year prospective clinical and patient-centered trial on subepithelial connective tissue graft with or without enamel matrix derivative in Class I-II Miller recessions., Journal of Periodontal Research, 2019
dcterms.dateAccepted2019-11-12
dc.date.updated2019-12-11T01:11:22Z
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version
gro.hasfulltextNo Full Text
gro.griffith.authorHamlet, Stephen


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