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dc.contributor.authorJayaraj, Rama
dc.contributor.authorKumarasamy, Chellan
dc.contributor.authorSabarimurugan, Shanthi
dc.contributor.authorBaxi, Siddhartha
dc.date.accessioned2019-12-12T04:08:50Z
dc.date.available2019-12-12T04:08:50Z
dc.date.issued2019
dc.identifier.issn1664-042X
dc.identifier.doi10.3389/fphys.2018.01896
dc.identifier.urihttp://hdl.handle.net/10072/389726
dc.description.abstractLiu et al. have recently published a paper highlighting blood-derived miRNAs as possible early diagnostic biomarkers in Pancreatic Cancer by conducting a narrative review and meta-analysis titled, “Blood-Derived microRNAs for Pancreatic Cancer Diagnosis: A Narrative Review and Meta-Analysis” (Li et al., 2018). Considering the extreme aggressiveness and malignancy associated with Pancreatic Cancer, combined with its poor prognosis and survival rates, and the dependence of diagnosis on non-specific tumor biomarkers, Liu et al.'s study highlighting possible alternative biomarkers, is definitely one that is of great clinical value (Benzel and Fendrich, 2018). However there are a few issues with this study that may serve to hinder its practical clinical applicability. First and foremost, in fairness we would like to highlight that Liu and associates are not the first to attempt to determine the applicability of miRNAs as diagnostic biomarkers in Pancreatic Cancer, multiple such meta-analysis studies have been conducted and published in 2012, 2014, 2017 (and have not been cited by the authors of this study) and even in May of 2018 (Wan et al., 2012; Ding et al., 2014; Pei et al., 2017; Sun et al., 2018).
dc.languageEnglish
dc.language.isoeng
dc.publisherFrontiers Media
dc.relation.ispartofjournalFrontiers in Physiology
dc.relation.ispartofvolume9
dc.subject.fieldofresearchMedical Physiology
dc.subject.fieldofresearchPhysiology
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchcode1116
dc.subject.fieldofresearchcode0606
dc.subject.fieldofresearchcode1701
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsmiRNAs
dc.subject.keywordsmeta-analysis
dc.titleCommentary: Blood-Derived microRNAs for Pancreatic Cancer Diagnosis: A Narrative Review and Meta-Analysis
dc.typeJournal article
dc.type.descriptionC2 - Articles (Other)
dcterms.bibliographicCitationJayaraj, R; Kumarasamy, C; Sabarimurugan, S; Baxi, S, Commentary: Blood-Derived microRNAs for Pancreatic Cancer Diagnosis: A Narrative Review and Meta-Analysis, Frontiers in Physiology, 2019, 9
dcterms.dateAccepted2018-12-18
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2019-12-12T03:56:51Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2019 Jayaraj, Kumarasamy, Sabarimurugan and Baxi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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gro.griffith.authorBaxi, Siddhartha


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