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dc.contributor.authorGundara, Justin S
dc.contributor.authorJamal, Karim
dc.contributor.authorKurzawinski, Tom
dc.date.accessioned2019-12-24T01:12:51Z
dc.date.available2019-12-24T01:12:51Z
dc.date.issued2018
dc.identifier.issn0303-7207
dc.identifier.doi10.1016/j.mce.2017.03.032
dc.identifier.urihttp://hdl.handle.net/10072/389945
dc.description.abstractPancreatic neuroendocrine tumours are a diverse group of neoplasms with an increasingly well-defined genomic basis. Despite this, much of what drives this disease is still unknown and epigenetic influences represent the next tier of gene, and hence disease modifiers that are of unquestionable importance. Moreover, they are of arguably more significance than the genes themselves given their malleable nature and potential to be exploited for not only diagnosis and prognosis, but also therapy. This review summarises what is known regarding the key epigenetic modifiers of disease through the domains of diagnosis, prognosis and treatment.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom85
dc.relation.ispartofpageto91
dc.relation.ispartofjournalMolecular and Cellular Endocrinology
dc.relation.ispartofvolume469
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchAgricultural, veterinary and food sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchcode31
dc.subject.fieldofresearchcode30
dc.subject.fieldofresearchcode32
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsCell Biology
dc.subject.keywordsEndocrinology & Metabolism
dc.subject.keywordsEpigenetic
dc.titleDictating genomic destiny: Epigenetic regulation of pancreatic neuroendocrine tumours
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationGundara, JS; Jamal, K; Kurzawinski, T, Dictating genomic destiny: Epigenetic regulation of pancreatic neuroendocrine tumours, Molecular and Cellular Endocrinology, 2018, 469, pp. 85-91
dcterms.dateAccepted2017-03-30
dc.date.updated2019-12-24T01:11:15Z
gro.hasfulltextNo Full Text
gro.griffith.authorGundara, Justin


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