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dc.contributor.authorRosewall, Tara
dc.contributor.authorBayley, Andrew J
dc.contributor.authorChung, Peter
dc.contributor.authorLe, Lisa W
dc.contributor.authorXie, Jason
dc.contributor.authorBaxi, Siddhartha
dc.contributor.authorCatton, Charles N
dc.contributor.authorCurrie, Geoffrey
dc.contributor.authorWheat, Janelle
dc.contributor.authorMilosevic, Michael
dc.date.accessioned2020-01-06T00:29:54Z
dc.date.available2020-01-06T00:29:54Z
dc.date.issued2011
dc.identifier.issn0167-8140
dc.identifier.doi10.1016/j.radonc.2011.06.039
dc.identifier.urihttp://hdl.handle.net/10072/390046
dc.description.abstractPURPOSE: To quantify the effect of delineation method on bladder DVH, observer variability (OV) and contouring time for prostate IMRT plans. MATERIALS AND METHODS: Planning CT scans and IMRT plans of 30 prostate cancer patients were anonymized. For 20 patients, 1 observer delineated the bladder using 9 methods. The effect of delineation method on the DVH curve, discrete dose levels and delineation time was quantified. For the 10 remaining CTs, 6 observers delineated bladder wall using 4 methods. Observer-based volume variation and intraclass correlation coefficient (ICC) were used to describe the dosimetric effects of OV. RESULTS: Manual delineation of the bladder wall (BW_m) was significantly slower than any other method (mean: 20 min vs. ≤ 13 min) and the dosimetric effect of OV was significantly larger (V70 Gy ICC: 0.78 vs. 0.98). Only volumes created using a 2.5mm contraction from the outer surface, and a method providing a consistent wall volume, showed no notable dosimetric differences from BW_m in both absolute and relative volume. CONCLUSIONS: Automatic contractions from the outer surface provide quicker, more reproducible and reasonably accurate substitutes for BW_m. The widespread use of automatic contractions to create a bladder wall volume would assist in the consistent application of IMRT dose constraints and the interpretation of reported dose.
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom479
dc.relation.ispartofpageto485
dc.relation.ispartofissue3
dc.relation.ispartofjournalRadiotherapy and Oncology
dc.relation.ispartofvolume101
dc.subject.fieldofresearchOther Physical Sciences
dc.subject.fieldofresearchOncology and Carcinogenesis
dc.subject.fieldofresearchcode0299
dc.subject.fieldofresearchcode1112
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsRadiology, Nuclear Medicine & Medical Imaging
dc.subject.keywordsOrgan at risk
dc.titleThe effect of delineation method and observer variability on bladder dose-volume histograms for prostate intensity modulated radiotherapy
dc.typeJournal article
dcterms.bibliographicCitationRosewall, T; Bayley, AJ; Chung, P; Le, LW; Xie, J; Baxi, S; Catton, CN; Currie, G; Wheat, J; Milosevic, M, The effect of delineation method and observer variability on bladder dose-volume histograms for prostate intensity modulated radiotherapy, Radiotherapy and Oncology, 2011, 101 (3), pp. 479-485
dcterms.dateAccepted2011-06-18
dc.date.updated2020-01-06T00:25:56Z
gro.hasfulltextNo Full Text
gro.griffith.authorBaxi, Siddhartha


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