Comment on "Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer" (Letter)

Jayaraj, Rama; Kumarasamy, Chellan; Madhav, Madurantakam Royam; Pandey, Venkatesh; Sabarimurugan, Shanthi; Ramesh, N; Gothandam, KM; Baxi, Siddhartha

doi:10.1155/2018/6904569

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Author(s)

Jayaraj, Rama

Kumarasamy, Chellan

Madhav, Madurantakam Royam

Pandey, Venkatesh

Sabarimurugan, Shanthi

Ramesh, N

Gothandam, KM

Baxi, Siddhartha

Griffith University Author(s)

Baxi, Siddhartha

Year published

2018

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Abstract

Pancreatic cancer is one of the most malignant and aggressive cancers, with poor survival rates and diagnosis being based on nonspecific tumour biomarkers. Due to this, the publication, “Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer”, by Sun et al. has excellent potential for highlighting potential miRNAs as high-accuracy diagnostic markers in pancreatic cancer [1]. However, we believe that despite the comprehensive study conducted by Sun et al., there are a few improvements that could be made to heighten the clinical utility of the paper further. As it stands, we ...
View more >Pancreatic cancer is one of the most malignant and aggressive cancers, with poor survival rates and diagnosis being based on nonspecific tumour biomarkers. Due to this, the publication, “Systematic Review and Meta-Analysis of Diagnostic Accuracy of miRNAs in Patients with Pancreatic Cancer”, by Sun et al. has excellent potential for highlighting potential miRNAs as high-accuracy diagnostic markers in pancreatic cancer [1]. However, we believe that despite the comprehensive study conducted by Sun et al., there are a few improvements that could be made to heighten the clinical utility of the paper further. As it stands, we believe that the study has some issues that prevent such applications of Sun et al.’s study.
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