• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Role OfOmega‐6 and Omega‐3 fatty acids in fetal programming

    Thumbnail
    View/Open
    Shrestha318975-Accepted.pdf (4.362Mb)
    File version
    Accepted Manuscript (AM)
    Author(s)
    Shrestha, Nirajan
    Sleep, Simone L
    Cuffe, James Sm
    Holland, Olivia J
    Perkins, Anthony V
    Yu Yau, Suk
    McAinch, Andrew J
    Hryciw, Deanne H
    Griffith University Author(s)
    Holland, Olivia J.
    Hryciw, D
    Hryciw, Deanne
    Year published
    2019
    Metadata
    Show full item record
    Abstract
    Maternal nutrition plays a critical role in fetal development and can influence adult onset of disease. Linoleic acid (LA) and alpha- linolenic acid (ALA) are major omega-6 (n-6) and n-3 polyunsaturated fatty acids (PUFA), respectively, that are essential in our diet. LA and ALA are critical for the development of the fetal neurological and immune systems. However, in recent years, the consumption of n-6 PUFA has increased gradually worldwide, and elevated n-6 PUFA consumption may be harmful to human health. Consumption of diets with high levels of n-6 PUFA before or during pregnancy may have detrimental effects on fetal ...
    View more >
    Maternal nutrition plays a critical role in fetal development and can influence adult onset of disease. Linoleic acid (LA) and alpha- linolenic acid (ALA) are major omega-6 (n-6) and n-3 polyunsaturated fatty acids (PUFA), respectively, that are essential in our diet. LA and ALA are critical for the development of the fetal neurological and immune systems. However, in recent years, the consumption of n-6 PUFA has increased gradually worldwide, and elevated n-6 PUFA consumption may be harmful to human health. Consumption of diets with high levels of n-6 PUFA before or during pregnancy may have detrimental effects on fetal development, and may influence overall health of offspring in adulthood. This review discusses the role of n-6 PUFA in fetal programming, the importance of a balance between n-6 and n-3 PUFAs in the maternal diet, and the need of further animal models and human studies that critically evaluate both n-6 and n-3 PUFA content in diets.
    View less >
    Journal Title
    Clinical and Experimental Pharmacology and Physiology
    DOI
    https://doi.org/10.1111/1440-1681.13244
    Copyright Statement
    © 2019 The Authors and Blackwell Publishing Asia Pty Ltd. This is the peer reviewed version of the following article: Role OfOmega‐6 and Omega‐3 fatty acids in fetal programming, Clinical and Experimental Pharmacology and Physiology, 2019, which has been published in final form at https://doi.org/10.1111/1440-1681.13244. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html)
    Note
    This publication has been entered into Griffith Research Online as an Advanced Online Version
    Subject
    Zoology
    Pharmacology and pharmaceutical sciences
    Medical physiology
    Clinical sciences
    Essential fatty acid
    fetal programming
    linoleic acid
    maternal nutrition
    sex ratio
    Publication URI
    http://hdl.handle.net/10072/390066
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E
    • TEQSA: PRV12076

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander