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dc.contributor.authorPollock, W
dc.contributor.authorPeek, MJ
dc.contributor.authorWang, A
dc.contributor.authorLi, Z
dc.contributor.authorEllwood, D
dc.contributor.authorHomer, CSE
dc.contributor.authorJackson Pulver, L
dc.contributor.authorMcLintock, C
dc.contributor.authorVaughan, G
dc.contributor.authorKnight, M
dc.contributor.authorSullivan, EA
dc.date.accessioned2020-01-13T06:18:55Z
dc.date.available2020-01-13T06:18:55Z
dc.date.issued2019
dc.identifier.issn0004-8666
dc.identifier.doi10.1111/ajo.13100
dc.identifier.urihttp://hdl.handle.net/10072/390175
dc.description.abstractBackground: Eclampsia is a serious consequence of pre-eclampsia. There are limited data from Australia and New Zealand (ANZ) on eclampsia. Aim: To determine the incidence, management and perinatal outcomes of women with eclampsia in ANZ. Materials and Methods: A two-year population-based descriptive study, using the Australasian Maternity Outcomes Surveillance System (AMOSS), carried out in 263 sites in Australia, and all 24 New Zealand maternity units, during a staggered implementation over 2010–2011. Eclampsia was defined as one or more seizures during pregnancy or postpartum (up to 14 days) in any woman with clinical evidence of pre-eclampsia. Results: Of 136 women with eclampsia, 111 (83%) were in Australia and 25 (17%) in New Zealand. The estimated incidence of eclampsia was 2.2 (95% confidence interval (CI) 1.9–2.7) per 10 000 women giving birth. Aboriginal and Torres Strait Islander women were over-represented in Australia (n = 9; 8.1%). Women with antepartum eclampsia (n = 58, 42.6%) were more likely to have a preterm birth (P = 0.04). Sixty-three (47.4%) women had pre-eclampsia diagnosed prior to their first eclamptic seizure of whom 19 (30.2%) received magnesium sulphate prior to the first seizure. Nearly all women (n = 128; 95.5%) received magnesium sulphate post-seizure. No woman received prophylactic aspirin during pregnancy. Five women had a cerebrovascular haemorrhage, and there were five known perinatal deaths. Conclusions: Eclampsia is an uncommon consequence of pre-eclampsia in ANZ. There is scope to reduce the incidence of this condition, associated with often catastrophic morbidity, through the use of low-dose aspirin and magnesium sulphate in women at higher risk.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.publisher.placeAustralia
dc.relation.ispartofjournalAustralian and New Zealand Journal of Obstetrics and Gynaecology
dc.subject.fieldofresearchHealth services and systems
dc.subject.fieldofresearchPublic health
dc.subject.fieldofresearchcode4203
dc.subject.fieldofresearchcode4206
dc.subject.keywordseclampsia
dc.subject.keywordsmaternal morbidity
dc.subject.keywordspre-eclampsia
dc.subject.keywordspregnancy
dc.subject.keywordsseizure
dc.titleEclampsia in Australia and New Zealand: A prospective population-based study
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationPollock, W; Peek, MJ; Wang, A; Li, Z; Ellwood, D; Homer, CSE; Jackson Pulver, L; McLintock, C; Vaughan, G; Knight, M; Sullivan, EA, Eclampsia in Australia and New Zealand: A prospective population-based study, Australian and New Zealand Journal of Obstetrics and Gynaecology, 2019
dcterms.dateAccepted2019-10-10
dc.date.updated2020-01-08T02:06:32Z
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version
gro.hasfulltextNo Full Text
gro.griffith.authorEllwood, David A.


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