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dc.contributor.authorIrani, Soussan
dc.date.accessioned2020-01-14T00:11:42Z
dc.date.available2020-01-14T00:11:42Z
dc.date.issued2019
dc.identifier.issn2008-3866
dc.identifier.doi10.22038/ijbms.2019.32786.7839
dc.identifier.urihttp://hdl.handle.net/10072/390188
dc.description.abstractMetastasis means the dissemination of the cancer cells from one organ to another which is not directly connected to the primary site. Metastasis has a crucial role in the prognosis of cancer patients. A few theories, different types of cell and several molecular pathways have been proposed to explain the mechanism of metastasis. In this work, the related articles in the limited period of time, 2000–mid -2018 were reviewed, through search in PubMed, Google Scholar and Scopus database. The articles published in the last two decades related to the biology of cancer metastasis were selected and the most important factors were discussed. Metastasis is critical factor to predict survival in patients with advanced cancer and prognosis determines the treatment plan. Many different cell types and various signaling pathways control the metastatic process. Metastasis is a multistep process. Many signaling pathways and molecules are involved in metastasis. Increasing knowledge about the mechanism of metastasis can help in finding the promising targets of cancer therapy.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherMashhad University of Medical Sciences
dc.relation.ispartofpagefrom833
dc.relation.ispartofpageto847
dc.relation.ispartofissue8
dc.relation.ispartofjournalIranian Journal of Basic Medical Sciences
dc.relation.ispartofvolume22
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3203
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsMedicine, Research & Experimental
dc.subject.keywordsPharmacology & Pharmacy
dc.subject.keywordsResearch & Experimental Medicine
dc.titleEmerging insights into the biology of metastasis: A review article
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationIrani, S, Emerging insights into the biology of metastasis: A review article, Iranian Journal of Basic Medical Sciences, 2019, 22 (8), pp. 833-847
dc.date.updated2020-01-14T00:09:35Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2019 Mashhad University of Medical Sciences. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.hasfulltextFull Text
gro.griffith.authorIrani, Soussan


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