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dc.contributor.authorRojas-Macias, Miguel A
dc.contributor.authorMariethoz, Julien
dc.contributor.authorAndersson, Peter
dc.contributor.authorJin, Chunsheng
dc.contributor.authorVenkatakrishnan, Vignesh
dc.contributor.authorAoki, Nobuyuki P
dc.contributor.authorShinmachi, Daisuke
dc.contributor.authorAshwood, Christopher
dc.contributor.authorMadunic, Katarina
dc.contributor.authorZhang, Tao
dc.contributor.authorMiller, Rebecca L
dc.contributor.authorHorlacher, Oliver
dc.contributor.authorStruwe, Weston B
dc.contributor.authorWatanabe, Yu
dc.contributor.authorOkuda, Shujiro
dc.contributor.authorLevander, Fredrik
dc.contributor.authorKolarich, Daniel
dc.contributor.authorRudd, Pauline M
dc.contributor.authorWuhrer, Manfred
dc.contributor.authorKettner, Carsten
dc.contributor.authorPacker, Nicolle H
dc.contributor.authorAoki-Kinoshita, Kiyoko F
dc.contributor.authorLisacek, Frederique
dc.contributor.authorKarlsson, Niclas G
dc.date.accessioned2020-01-30T04:46:39Z
dc.date.available2020-01-30T04:46:39Z
dc.date.issued2019
dc.identifier.issn2041-1723
dc.identifier.doi10.1038/s41467-019-11131-x
dc.identifier.urihttp://hdl.handle.net/10072/390989
dc.description.abstractThe mass spectrometry (MS)-based analysis of free polysaccharides and glycans released from proteins, lipids and proteoglycans increasingly relies on databases and software. Here, we review progress in the bioinformatics analysis of protein-released N- and O-linked glycans (N- and O-glycomics) and propose an e-infrastructure to overcome current deficits in data and experimental transparency. This workflow enables the standardized submission of MS-based glycomics information into the public repository UniCarb-DR. It implements the MIRAGE (Minimum Requirement for A Glycomics Experiment) reporting guidelines, storage of unprocessed MS data in the GlycoPOST repository and glycan structure registration using the GlyTouCan registry, thereby supporting the development and extension of a glycan structure knowledgebase.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherNature Publishing Group
dc.relation.ispartofissue1
dc.relation.ispartofjournalNature Communications
dc.relation.ispartofvolume10
dc.subject.fieldofresearchBiological Sciences
dc.subject.fieldofresearchcode06
dc.subject.keywordsScience & Technology
dc.subject.keywordsMultidisciplinary Sciences
dc.subject.keywordsScience & Technology - Other Topics
dc.subject.keywordsMASS-SPECTROMETRY
dc.subject.keywordsMINIMUM INFORMATION
dc.titleTowards a standardized bioinformatics infrastructure for N- and O-glycomics
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationRojas-Macias, MA; Mariethoz, J; Andersson, P; Jin, C; Venkatakrishnan, V; Aoki, NP; Shinmachi, D; Ashwood, C; Madunic, K; Zhang, T; Miller, RL; Horlacher, O; Struwe, WB; Watanabe, Y; Okuda, S; Levander, F; Kolarich, D; Rudd, PM; Wuhrer, M; Kettner, C; Packer, NH; Aoki-Kinoshita, KF; Lisacek, F; Karlsson, NG, Towards a standardized bioinformatics infrastructure for N- and O-glycomics, Nature Communications, 2019, 10 (1)
dcterms.dateAccepted2019-06-24
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2020-01-30T04:42:52Z
dc.description.versionPublished
gro.rights.copyright© The Author(s). 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
gro.hasfulltextFull Text
gro.griffith.authorKolarich, Daniel
gro.griffith.authorPacker, Nicki


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